LINC01414/LINC00824 genetic polymorphisms in association with the susceptibility of chronic obstructive pulmonary disease

Table 2 The information about the candidate SNPs and the association with COPD in the allele model

Gene	SNP ID	Chr: position	Alleles (Alt/Ref)	MAF		Call rate (%)	HWE			OR (95% CI)	p
Gene	SNP ID	Chr: position	Alleles (Alt/Ref)	Cases	Controls	Call rate (%)	O(HET)	E(HET)	p	OR (95% CI)	p
LINC01414	rs6994670	8:65,191,812	G/A	0.214	0.273	99.8	0.393	0.397	0.887	0.73 (0.56–0.94)	0.015*
LINC01414	rs298207	8:65,282,597	A/G	0.229	0.189	98.4	0.320	0.307	0.578	1.27 (0.97–1.68)	0.086
LINC00824	rs7815944	8:129,427,518	G/A	0.265	0.304	99.8	0.390	0.423	0.181	0.83 (0.65–1.06)	0.131

Bold indicate that p < 0.05 means the data is statistically significant
COPD chronic obstructive pulmonary disease, SNP single nucleotide polymorphism, MAF minor allele frequency, HWE Hardy–Weinberg equilibrium, O(HET) observed heterozygotes, E(HET) expected heterozygotes

ISSN: 1471-2466