SNP ID | Model | Genotype | Case | Control | OR (95%CI) | p | Case | Control | OR (95%CI) | p |
---|---|---|---|---|---|---|---|---|---|---|
Age | > 70 years | ≤ 70 years | ||||||||
LINC01414 rs6994670 | Allele | A | 297 | 268 | 1 | 198 | 187 | 1 | ||
G | 79 | 84 | 0.85 (0.60–1.20) | 0.356 | 56 | 87 | 0.61 (0.41–0.90) | 0.012* | ||
Genotype | AA | 116 | 102 | 1 | 78 | 64 | 1 | |||
AG | 65 | 64 | 0.94 (0.59–1.47) | 0.776 | 42 | 59 | 0.57 (0.33–0.97) | 0.037* | ||
GG | 7 | 10 | 0.56 (0.20–1.57) | 0.271 | 7 | 14 | 0.33 (0.12–0.90) | 0.031* | ||
Dominant | AA | 116 | 102 | 1 | 78 | 64 | 1 | |||
AG-GG | 72 | 74 | 0.88 (0.57–1.36) | 0.569 | 49 | 73 | 0.52 (0.31–0.86) | 0.012* | ||
Recessive | AA-AG | 181 | 166 | 1 | 120 | 123 | 1 | |||
GG | 7 | 10 | 0.57 (0.21–1.59) | 0.285 | 7 | 14 | 0.42 (0.16–1.12) | 0.083 | ||
Log-additive | – | 0.85 (0.59–1.23) | 0.385 | 0.57 (0.38–0.86) | 0.007* | |||||
LINC01414 rs298207 | Allele | G | 294 | 287 | 1 | 184 | 214 | 1 | ||
A | 78 | 63 | 1.21 (0.84–1.75) | 0.315 | 64 | 54 | 1.38 (0.91–2.08) | 0.126 | ||
Genotype | GG | 118 | 119 | 1 | 74 | 82 | 1 | |||
GA | 58 | 49 | 1.24 (0.77–2.00) | 0.379 | 36 | 50 | 0.84 (0.48–1.44) | 0.521 | ||
AA | 10 | 7 | 1.40 (0.50–3.90) | 0.522 | 14 | 2 | 7.94 (1.69–37.21) | 0.009* | ||
Dominant | GG | 118 | 119 | 1 | 74 | 82 | 1 | |||
GA-AA | 68 | 56 | 1.26 (0.80–1.98) | 0.317 | 50 | 52 | 1.1 (0.66–1.83) | 0.726 | ||
Recessive | GG-GA | 176 | 168 | 1 | 110 | 132 | 1 | |||
AA | 10 | 7 | 1.31 (0.47–3.62) | 0.602 | 14 | 2 | 8.47 (1.83–39.24) | 0.006* | ||
Log-additive | –- | 1.21 (0.83–1.76) | 0.311 | 1.38 (0.91–2.11) | 0.134 | |||||
LINC00824 rs7815944 | Allele | A | 278 | 235 | 1 | 185 | 201 | 1 | ||
G | 98 | 117 | 0.71 (0.51–0.97) | 0.034* | 69 | 73 | 1.03 (0.70–1.51) | 0.892 | ||
Genotype | AA | 99 | 82 | 1 | 69 | 75 | 1 | |||
AG | 80 | 71 | 0.90 (0.57–1.42) | 0.653 | 47 | 51 | 1.02 (0.60–1.72) | 0.951 | ||
GG | 9 | 23 | 0.29 (0.12–0.68) | 0.005* | 11 | 11 | 1.03 (0.40–2.61) | 0.956 | ||
Dominant | AA | 99 | 82 | 1 | 69 | 75 | 1 | |||
AG-GG | 89 | 94 | 0.75 (0.49–1.16) | 0.193 | 58 | 62 | 1.02 (0.62–1.67) | 0.943 | ||
Recessive | AA-AG | 179 | 153 | 1 | 116 | 126 | 1 | |||
GG | 9 | 23 | 0.30 (0.13–0.70) | 0.005* | 11 | 11 | 1.02 (0.41–2.53) | 0.966 | ||
Log-additive | – | 0.68 (0.48–0.95) | 0.023* | 1.02 (0.69–1.49) | 0.941 | |||||
Gender | Male | Female | ||||||||
LINC01414 rs298207 | Allele | G | 367 | 379 | 1 | 111 | 122 | 1 | ||
A | 107 | 91 | 1.21 (0.89–1.66) | 0.226 | 35 | 26 | 1.48 (0.84–2.61) | 0.176 | ||
Genotype | GG | 147 | 151 | 1 | 45 | 50 | 1 | |||
GA | 73 | 77 | 0.98 (0.66–1.46) | 0.932 | 21 | 22 | 1.06 (0.51–2.18) | 0.878 | ||
AA | 17 | 7 | 2.53 (1.02–6.28) | 0.046* | 7 | 2 | 3.99 (0.77–20.64) | 0.099 | ||
Dominant | GG | 147 | 151 | 1 | 45 | 50 | 1 | |||
GA-AA | 90 | 84 | 1.11 (0.76–1.62) | 0.582 | 28 | 24 | 1.29 (0.66–2.55) | 0.456 | ||
Recessive | GG-GA | 220 | 228 | 1 | 66 | 72 | 1 | |||
AA | 17 | 7 | 2.54 (1.03–6.26) | 0.043* | 7 | 2 | 3.92 (0.77–20.00) | 0.101 | ||
Log-additive | – | 1.22 (0.89–1.66) | 0.218 | 1.43 (0.82–2.46) | 0.204 | |||||
LINC00824 rs7815944 | Allele | A | 362 | 331 | 1 | 101 | 105 | 1 | ||
G | 116 | 141 | 0.75 (0.56–1.00) | 0.052 | 51 | 49 | 1.08 (0.67–1.75) | 0.746 | ||
Genotype | AA | 134 | 118 | 1 | 34 | 39 | 1 | |||
AG | 94 | 95 | 0.87 (0.59–1.26) | 0.454 | 33 | 27 | 1.41 (0.71–2.81) | 0.332 | ||
GG | 11 | 23 | 0.43 (0.20–0.91) | 0.028* | 9 | 11 | 0.94 (0.35–2.58) | 0.912 | ||
Dominant | AA | 134 | 118 | 1 | 34 | 39 | 1 | |||
AG-GG | 105 | 118 | 0.78 (0.54–1.12) | 0.179 | 42 | 38 | 1.28 (0.67–2.43) | 0.457 | ||
Recessive | AA-AG | 228 | 213 | 1 | 67 | 66 | 1 | |||
GG | 11 | 23 | 0.45 (0.22–0.96) | 0.037* | 9 | 11 | 0.81 (0.31–2.08) | 0.655 | ||
Log-additive | – | 0.75 (0.56–1.00) | 0.052 | 1.08 (0.68–1.71) | 0.753 |