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Table 8 Association of clinical characteristics with genotypes of candidate SNPs among COPD patients

From: LINC01414/LINC00824 genetic polymorphisms in association with the susceptibility of chronic obstructive pulmonary disease

Variables

LINC01414 rs6994670

AA

AG

GG

p

Respiratory rate, times/min

22.24 ± 2.35

22.49 ± 2.73

21.70 ± 1.57

0.519

Pulse rate, times/min

86.50 ± 11.07

86.86 ± 12.81

78.20 ± 7.63

0.078

FVC, L

2.01 ± 0.71

1.90 ± 0.66

2.03 ± 0.42

0.665

FEV1, L

1.23 ± 0.57

1.20 ± 0.68

1.20 ± 0.41

0.932

FEV1/FVC, %

52.18 ± 11.83

48.55 ± 11.23

57.65 ± 13.46

0.133

Variables

LINC01414 rs298207

AA

GA

GG

p

Respiratory rate, times/min

22.15 ± 2.94

22.29 ± 2.43

22.37 ± 2.46

0.914

Pulse rate, times/min

85.05 ± 13.57

87.86 ± 12.44

85.81 ± 11.12

0.357

FVC, L

2.00 ± 0.64

1.89 ± 0.56

2.02 ± 0.75

0.555

FEV1, L

1.28 ± 0.54

1.13 ± 0.48

1.27 ± 0.67

0.384

FEV1/FVC, %

5086 ± 15.95

53.44 ± 210.66

50.27 ± 11.99

0.387

Variables

LINC00824 rs7815944

AA

AG

GG

p

Respiratory rate, times/min

22.36 ± 2.5

22.48 ± 2.49

20.78 ± 1.26

0.022

Pulse rate, times/min

86.22 ± 11.12

86.32 ± 12.28

87.28 ± 12.86

0.937

FVC, L

1.98 ± 0.61

2.00 ± 0.76

1.84 ± 0.77

0.777

FEV1, L

1.19 ± 0.52

1.22 ± 0.65

1.41 ± 0.81

0.489

FEV1/FVC, %

52.35 ± 11.23

50.34 ± 12.04

50.46 ± 16.01

0.657

  1. p values were calculated by Analysis of Variance (ANOVA)
  2. Bold indicate that p < 0.05 indicates statistical significance
  3. COPD chronic obstructive pulmonary disease, BMI body mass index, FVC including forced vital capacity, FEV1 forced the first second of expiratory volume