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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: Long non-coding RNA OIP5-AS1 aggravates acute lung injury by promoting inflammation and cell apoptosis via regulating the miR-26a-5p/TLR4 axis

Fig. 5

OIP5-AS1 regulated miR-26a-5p in ALI. A The expression of predicted lncRNAs in lung tissues from sham and ALI groups. B The predicted biding sites of miR-26a-5p on OIP5-AS1. C, D The interaction between miR-26a-5p and OIP5-AS1 was demonstrated by luciferase reporter and RIP assays. #P < 0.05 compared with NC group or anti-IgG group. E The effects of overexpressed OIP5-AS1 on miR-26a-5p expression were estimated by RT-qPCR. #P < 0.05 compared with NC group. F, G RT-qPCR analysis was conducted to evaluate the level of OIP5-AS1 in lung tissues of ALI mice and sham mice (n = 8 per group) and in LPS-stimulated PBECs. #P < 0.05 compared with sham group or control group

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BMC Pulmonary Medicine

ISSN: 1471-2466

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