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Table 5 Comparison of clinical and demographic characteristics between antifibrotic drug-treated group and non-treated group in JRS stage I with oxygen desaturation on the 6MWT

From: Efficacy of early antifibrotic treatment for idiopathic pulmonary fibrosis

 

Non-treated group

Treated group

P value

Age, years

71.4 ± 6.7

71.2 ± 6.9

0.91

Sex, male/female

28/9

40/8

0.42

Smoking history, N/F/C

4/26/7

5/31/12

0.44

GAP staging (I/II/III)

15/18/4

17/26/5

0.27

PaO2, Torr

89.1 ± 7.9

87.1 ± 7.0

0.22

%FVC, %

76.1 ± 19.7

70.0 ± 14.4

0.10

%DLco, %

58.7 ± 18.0

58.0 ± 18.3

0.85

KL-6, U/ml

1006 ± 543

1181 ± 678

0.20

SP-D, ng/ml

319 ± 247

331 ± 285

0.83

6MWD, m

365 ± 108

380 ± 102

0.50

Lowest SpO2 on 6MWT, %

86.9 ± 3.1

88.2 ± 5.0

0.16

  1. Data is presented as mean ± standard deviation. JRS, Japanese Respiratory Society; N/F/C, never/former/current; GAP, gender–age–physiology; PaO2, partial pressure of oxygen in arterial blood; FVC, forced vital capacity; DLco, diffusion capacity of the lungs for carbon monoxide; KL-6, Krebs von den Lungen-6; SP-D, surfactant protein-D; 6MWD, 6-min walking distance; SpO2, percutaneous oxygen saturation; 6MWT, 6-min walk test