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Table 6 Comparison of clinical and demographic characteristics between antifibrotic drug-treated group and non-treated group in JRS stage I with GAP stage II/III

From: Efficacy of early antifibrotic treatment for idiopathic pulmonary fibrosis

 

Non-treated group

Treated group

P value

Age, years

72.2 ± 5.4

73.2 ± 7.1

0.55

Sex, male/female

29/3

34/5

0.72

Smoking history, N/F/C

5/23/4

4/30/5

0.79

GAP staging (I/II/III)

0/27/5

0/32/7

0.62

PaO2, Torr

88.1 ± 9.8

87.9 ± 7.7

0.91

%FVC, %

68.2 ± 15.8

62.9 ± 13.5

0.13

%DLco, %

54.8 ± 21.2

55.0 ± 15.2

0.95

KL-6, U/ml

971 ± 660

1108 ± 699

0.40

SP-D, ng/ml

308 ± 291

348 ± 297

0.57

6MWD, m

351 ± 89

349 ± 101

0.92

Lowest SpO2 on 6MWT, %

89.4 ± 4.0

89.0 ± 5.4

0.76

  1. Data is presented as mean ± standard deviation. JRS, Japanese Respiratory Society; N/F/C, never/former/current; GAP, gender–age–physiology; PaO2, partial pressure of oxygen in arterial blood; FVC, forced vital capacity; DLco, diffusion capacity of the lungs for carbon monoxide; KL-6, Krebs von den Lungen-6; SP-D, surfactant protein-D; 6MWD, 6-min walking distance; SpO2, percutaneous oxygen saturation; 6MWT, 6-min walk test