|
Body mass index, kg/m2 n = 473
|
|
< 18.5
|
195 (55.9)
|
50.6, 61.0
|
81 (65.3)
|
56.5, 73.2
|
|
18.5–24.9
|
142 (40.7)
|
35.6, 45.9
|
39 (31.5)
|
23.8, 40.2
|
|
25.0–29.9
|
12 (3.4)
|
2.0, 6.0
|
4 (3.2)
|
1.2, 8.4
|
|
History of TB treatment
|
|
Yes
|
556 (59.6)
|
56.4, 62.7
|
107 (56.6)
|
49.4, 63.5
|
|
No
|
377 (40.4)
|
37.3, 43.6
|
82 (43.4)
|
36.5, 50.6
|
|
HIV Status
| | | | |
|
Positive
|
564 (60.5)
|
57.3, 63.5
|
102 (54)
|
46.8, 61.0
|
|
Negative
|
369 (39.5)
|
36.5, 42.7
|
87 (46)
|
39.0, 53.2
|
|
Cotrimoxazole use, n = 603
|
|
Yes
|
491 (97)
|
95.1, 98.2
|
96 (99)
|
92.9, 99.9
|
|
No
|
15 (3)
|
1.8, 4.9
|
1 (1)
|
0.1, 7.1
|
|
ART use, n = 655
|
|
Yes
|
521 (94)
|
91.7, 95.7
|
101 (100)
|
-
|
|
No
|
33 (6)
|
4.3, 8.3
|
0 (0)
|
-
|
|
History of ART default, n = 491
|
|
Yes
|
60 (14.7)
|
11.6, 18.5
|
26 (31)
|
21.9, 41.8
|
|
No
|
347 (85.3)
|
81.5, 88.4
|
58 (69)
|
58.2, 78.1
|
|
Diabetes, n = 151
| | | | |
|
Yes
|
36 (33)
|
24.8, 42.5
|
12 (28.6)
|
16.7, 44.4
|
|
No
|
73 (67)
|
57.5, 75.2
|
30 (71.4)
|
55.6, 83.3
|
|
Hypertension, n = 479
|
|
Yes
|
19 (4.6)
|
2.9, 7.0
|
5 (8.1)
|
3.3, 18.2
|
|
No
|
398 (95.4)
|
93.0, 97.1
|
57 (91.9)
|
81.8, 96.7
|
|
Systolic blood pressure, n = 479
|
|
< 90
|
32 (7.7)
|
5.5, 10.7
|
10 (16.1)
|
8.8, 28.7
|
|
90–140
|
375 (89.9)
|
86.6, 92.5
|
48 (77.4)
|
65.1, 86.3
|
|
> 140
|
10 (2.4)
|
1.3, 4.4
|
4 (6.5)
|
2.4, 16.2
|
|
Diastolic blood pressure, n = 479
|
|
< 60
|
41 (9.8)
|
7.3, 13.1
|
10 (16.1)
|
8.8, 27.7
|
|
60–90
|
362 (86.8)
|
83.2, 89.7
|
51 (82.3)
|
70.5, 90.0
|
|
> 90
|
14 (3.4)
|
2.0, 5.6
|
1 (1.6)
|
0.2, 11.0
|
|
Cancer
|
|
No
|
919 (98.5)
|
97.5, 99.1
|
186 (98.4)
|
95.2, 99.5
|
|
Yes
|
14 (1.5)
|
0.9, 2.5
|
3 (1.6)
|
0.5, 4.8
|
|
Elevated creatinine†, n = 934
|
|
Yes
|
231 (29.4)
|
26.3, 32.6
|
48 (32.7)
|
25.5, 40.7
|
|
No
|
556 (70.6)
|
67.4, 73.7
|
99 (67.3)
|
59.3, 74.5
|
|
Hepatic injury§, n = 928
|
|
Yes
|
639 (82.8)
|
79.9, 85.3
|
141 (90.4)
|
84.6, 94.1
|
|
No
|
133 (17.2)
|
14.7, 20.1
|
15 (9.6)
|
5.9, 15.4
|
|
Hearing impairment, n = 803
|
|
Normal Hearing
|
351 (54.5)
|
50.6, 58.3
|
93 (58.5)
|
50.6, 65.9
|
|
Low Frequency
|
113 (17.5)
|
14.8, 20.7
|
24 (15.1)
|
10.3, 21.6
|
|
High Frequency
|
180 (28)
|
24.6, 31.6
|
42 (26.4)
|
20.1, 33.9
|
|
Distribution of hearing loss, n = 348
|
|
Bilateral hearing loss
|
233 (80.9)
|
75.9, 85.1
|
55 (91.7)
|
81.2, 96.6
|
|
Unilateral hearing loss
|
55 (19.1)
|
14.9, 24.1
|
5 (8.3)
|
3.4, 18.8
|
|
Grade of hearing loss, n = 314
|
|
Mild
|
145 (55.3)
|
49.2, 61.3
|
20 (38.5)
|
26.1, 52.6
|
|
Moderate
|
65 (24.8)
|
19.9, 30.4
|
18 (34.6)
|
22.8, 48.7
|
|
Severe
|
34 (13)
|
9.4, 17.6
|
9 (17.3)
|
9.1, 30.4
|
|
Profound
|
18 (6.9)
|
4.4, 10.7
|
5 (9.6)
|
4.0, 21.5
|
|
Psychiatric symptoms
|
|
Yes
|
49 (5.3)
|
4.0, 6.9
|
20 (10.6)
|
6.9, 15.9
|
|
No
|
884 (94.7)
|
93.1, 96.0
|
169 (89.4)
|
84.1, 93.1
|
|
Resistance to SLDs
|
|
Yes
|
4 (0.4)
|
0.1, 1.1
|
9 (4.8)
|
2.5, 8.9
|
|
No
|
929 (99.6)
|
98.9, 99.8
|
180 (95.2)
|
91.1, 97.5
|
|
Previous exposure to SLDS
|
|
Yes
|
17 (1.8)
|
1.1, 2.9
|
13 (6.9)
|
4.0, 11.5
|
|
No
|
916 (98.2)
|
97.1, 98.9
|
176 (93.1)
|
88.5, 96.0
|
