Table 1 Clinicopathological data in MCD and IgG4-LD
From: IL-6 expression helps distinguish Castleman’s disease from IgG4-related disease in the lung
Diagnosis | Material | Age | Sex | Serum IgG4 (mg/dL) | Serum IL-6 (pg/mL) | IL-6 H-score | IgG4/IgG ratio | Past histoly and comorbidities | Corticosteroid treatment | Tocilizumab treatment | |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | MCD | Resected | 34 | M | 290 | 99.4 | 12.16 | 31.3 | Hepatosplenomegaly | No | Yes* |
2 | MCD | Resected | 40 | M | 961 | na | 23.68 | 29.3 | None | No | No |
3 | MCD | Resected | 43 | M | 490 | 25.3 | 10.66 | 29.4 | Cardiac hypofunction, diabetes mellitus | Yes* | No |
4 | MCD | Biopsied | 46 | F | 318 | 26.6 | na | 14.0 | None | No | No |
5 | MCD | Biopsied | 65 | F | 147 | 10.1 | 3.70 | 57.1 | Thymoma | No | No |
6 | MCD | Biopsied | 40 | M | 269 | 17.9 | 11.59 | 59.1 | None | Yes | Yes* |
7 | IgG4-LD | Resected | 66 | M | 227 | 3.22 | 7.76 | 70.5 | Diabetes mellitus | No | No |
8 | IgG4-LD | Resected | 78 | M | 322 | 1.76 | 10.43 | 59.5 | Emphysema, pulmonary fibrosis | No | No |
9 | IgG4-LD | Biopsied | 71 | F | 1714 | 1.83 | 3.45 | 93.8 | IgG4-RD (peritoneum and left orbit) | Yes* | No |
10 | IgG4-LD | Biopsied | 67 | M | 605 | 0.523 | 0.00 | 91.1 | IgG4-RD (pancreas and bile duct) | Yes* | No |