Table 1 Baseline characteristics
Variable | Total (N = 74) | ILDs (N = 36) | ILDd (N = 38) | P value |
|---|---|---|---|---|
Age (years) | 59.47 ± 9.63 | 55.72 ± 9.94 | 63.00 ± 8.00 | 0.001 |
Women, n (%) | 39.19% | 55.56% | 23.68% | 0.005 |
Duration of disease (month) | 12 (2.8–48) | 6 (1–12) | 48 (12–72) | < 0.001 |
ILD subtypes, n (%) | ||||
IPF | 14 (18.9%) | 6 (16.7%) | 8 (21.1%) | |
Unclassifiable ILD | 26 (35.1%) | 13 (36.1%) | 13 (34.2%) | |
CTD-ILD | 23 (31.1%) | 10 (27.8%) | 13 (34.2%) | |
Idiopathic NSIP | 6 (8.1%) | 3 (8.3%) | 3 (7.9%) | |
HP | 5 (6.8%) | 4 (11.1%) | 1 (2.6%) | |
SBP (mmHg) | 127.55 ± 14.81 | 129.33 ± 13.54 | 125.87 ± 15.91 | 0.318 |
DBP (mmHg) | 77.77 ± 9.82 | 77.92 ± 9.21 | 77.63 ± 10.49 | 0.902 |
PaO2 (mmHg) | 75.78 ± 16.04 | 79.64 ± 14.35 | 71.81 ± 16.91 | 0.039 |
PaCO2 (mmHg) | 41.52 ± 7.37 | 41.5 (39.25–44.00) | 39.91 ± 5.68 | 0.092 |
SaPO2 (%) | 96 (91–97) | 96 (94–97) | 95 (90–96) | 0.034 |
NT-proBNP (pg/ml) | 50.56 (33.40–219.42) | 33.40 (23.74–47.96) | 125.00 (50.40–590.87) | < 0.001 |
FVC% | 77.86 ± 18.81 | 83.89 ± 16.58 | 71.1 ± 19.16 | 0.012 |
DLCO% | 51.74 ± 18.80 | 59.52 ± 16.71 | 43.06 ± 17.50 | 0.001 |
TLC% | 70.52 ± 17.12 | 77.20 ± 17.19 | 63.04 ± 13.89 | 0.002 |
ILD-GAP score | 2 (0–3) | 1 (-1–2) | 3 (1–4) | < 0.001 |