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Table 3 MVMR analysis results

From: Lung function, COPD and cognitive function: a multivariable and two sample Mendelian randomization study

Lung function measure Condition No SNPs (trait/condition) Cognitive function
Beta (SE) p-value
FEV1 None 298/0 − 0.06 (0.03) < 0.001
FEV1 Height 212/299 − 0.03 (0.03) 0.29
FEV1 BMI 180/629 − 0.07 (0.03) 0.03
FEV1 Educational attainment 274/32 − 0.03 (0.03) 0.33
FVC None 381/0 − 0.06 (0.01) < 0.001
FVC Height 278/314 − 0.01 (0.03) 0.62
FVC BMI 224/595 − 0.05 (0.02) 0.004
FVC Educational attainment 335/31 − 0.01 (0.02) 0.35
  1. Effect of decreasing Lung function trait on cognitive function with and without conditioning for covariates
  2. Negative beta indicates decreasing cognitive function
  3. SE, standard error