Table 2 Rate of on-treatment exacerbations for the UMEC/VI and TIO cohorts
COPD-related exacerbation outcomes | Number of events | Rate (per 100 person-days) | Rate ratio (95% CI) | p value | ||
|---|---|---|---|---|---|---|
UMEC/VI (N = 3929) | TIO (N = 3929) | UMEC/VI (N = 3929) | TIO (N = 3929) | |||
On-treatment period, mean (SD) [median] | 150.1 (135.5) [90] | 111.2 (116.6) [60] | – | - | – | – |
Total person-days | 589 596 | 436 824 | – | – | – | – |
Exacerbations | ||||||
 Overall | 698 | 541 | 0.12 | 0.12 | 0.95 (0.84, 1.07) | 0.473 |
 Moderate | 476 | 392 | 0.08 | 0.09 | 0.90 (0.77, 1.06) | 0.152 |
 Severe | 222 | 149 | 0.04 | 0.03 | 1.10 (0.85, 1.35) | 0.477 |