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Table 2 Correlations FRI versus CF-CT (n = 39)

From: Functional respiratory imaging in relation to classical outcome measures in cystic fibrosis: a cross-sectional study

FRI CF-CT scores (%)
BE Mucus BWT Parenchyma AT Total
iVlobe at TLC (L) NS NS NS − 0.17* NS NS
Sqrt of iVlobe at FRC (L) NS NS 0.18* NS NS NS
Log of siVaw at TLC (mL/L) 0.40*** NS 0.17* 0.26*** 0.23** 0.35***
Log of siVaww at TLC (mL/L) 0.30*** 0.16* 0.18* 0.36*** NS 0.30***
Cube root of siRaw at TLC (kPa * s/L) NS NS NS − 0.21** − 0.23** − 0.15*
AT at FRC (%) 0.37*** 0.35*** 0.29*** 0.21** 0.38*** 0.43***
Sqrt of TBV at TLC (mL/L) NS 0.41*** 0.16* 0.32*** NS 0.20*
Sqrt of BV10% at TLC (%) NS 0.19* NS 0.37*** NS 0.16*
BV5_10% at TLC (%) 0.55*** 0.43*** 0.50*** NS 0.41*** 0.57***
Square of BV5% at TLC (%) − 0.22** − 0.32*** − 0.26*** − 0.40*** − 0.22** − 0.34***
  1. Repeated measures correlation coefficients, *p < 0.05; **p < 0.01; ***p < 0.001
  2. iVlobe lobar volume, siVaw specific airway volume, siVaww specific airway wall volume, siRaw specific airway resistance, AT air trapping, TBV total pulmonary blood volume corrected for lobar volume, BV10% percentage of blood vessels larger than 10 mm2, BV5_10% percentage of blood vessels between 5 and 10 mm2, BV5% percentage of blood vessels smaller than 5 mm2, BE bronchiectasis, BWT bronchial wall thickening