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Table 8 Follow-up data of borderline PH, according to definition of PVR cut-off ≥ 3 WU

From: Characteristics of patients meeting the new definition of pre-capillary pulmonary hypertension (Nice 2018) in a single Japanese pulmonary hypertension center

Group Group of PH Background disease Age at diagnosis RHC at diagnosis Desition after first RHC RHC at final follow up Desition after final RHC Outcome
mPAP
(mmHg)
PVR
(WU)
PCWP
(mmHg)
mPAP
(mmHg)
PVR
(WU)
PCWP
(mmHg)
Boderline PH 1 SSc 37 22 2.6 5 Follow up 37 2.6 9 Ambrisentan Deceased because of lung cancer in 14 month
Boderline PH 3 COPD 65 23 2.6 5 Follow up 35 3.7 4 Treatment of COPD Became feasible because of COPD
Boderline PH 3 SSc + Fibrosis 35 20 1.2 11 Follow up 40 2.9 16 Treatment of left heart failure Deceased because of left heart failure in 11 month
Boderline PH 4 CTEPH 46 24 2.4 7 Follow up 19 1.1 10 Follow up Stable
Boderline pre-capillary PH 4 Aortitis 61 24 5.8 4 Follow up 29 7.7 1 Riociguat Improved after the treatment of riociguat
  1. SSc, Systemic sclerosis; COPD, Chronic obstructive pulmonary disease; CTEPH; Chronic thromboembolic pulmonary hypertension