Fig. 4

Blood neutrophil counts are increased in COPD patients with high comorbidities. WBC and differential counts in COPD patients with 0–1 comorbidities (L-Com) were compared with those in COPD patients with ≥ 2 comorbidities (H-Com) by statistical analysis. a Peripheral blood WBC counts were increased in COPD subjects with high comorbidities (H-Com) compared with those with low comorbidities (L-Com). *p = 0.012. b Moreover, neutrophil counts were greater in COPD subjects with H-Com than in those with L-Com. ***p < 0.001. c However, peripheral blood eosinophil counts were reduced in COPD subjects with H-Com. *p = 0.037. d The ratio of peripheral blood eosinophils/neutrophils was decreased in COPD subjects with H-Com. ***p < 0.001