From: Elevated levels of arginase activity are related to inflammation in patients with COPD exacerbation
N | Group (I)a | Group (II)a | Group (III)a | Group (IV)a | p I + II | p I + III | p II + III | p III + IV | p II + IV | |
---|---|---|---|---|---|---|---|---|---|---|
Actarginase (µmol urea/min) | 49 | 0.500 (0.122) | 0.521 (0.217) | 0.70 (0.33) | 0.59 (0.32) | 0.720 | 0.042 | 0.067 | 0.357 | 0.483 |
CRP (mg/L) | 49 | 0.551 (0.685) | 0.689 (0.750) | 1.283 (1.200) | 2.602 (3.110) | 0.445 | 0.027 | 0.061 | 0.038 | 0.147 |
IL-6 (pg/ml) | 37 | 13.45 (1.992) | 10.74 (1.040) | 14.54 (4.87) | 15.57 (2.58) | 0.001 | 0.522 | 0.037 | 0.643 | 0.005 |
IL-8 (pg/ml) | 37 | 64.53 (17.13) | 53.49 (9.65) | 69.86 (15.46) | 70.89 (17.70) | 0.081 | 0.475 | 0.008 | 0.904 | 0.018 |
TNF-a (pg/ml) | 37 | 100.0 (12.72) | 98.54 (12.95) | 95.70 (10.56) | 94.72 (18.75) | 0.797 | 0.421 | 0.591 | 0.902 | 0.660 |
INF-γ (pg/ml) | 37 | 58.22 (8.285) | 75.62 (25.29) | 89.30 (9.97) | 87.42 (4.96) | 0.051 | < 0.001 | 0.121 | 0.675 | 0.162 |
Neutrophils (%) | 49 | 61.57 (8.13) | 62.12 (7.60) | 78.76 (12.93) | 62.78 (10.18) | 0.841 | < 0.001 | < 0.001 | 0.001 | 0.832 |
Lymphocytes (%) | 49 | 28.85 (7.49) | 27.77 (7.35) | 15.31 (9.48) | 27.47 (8.92) | 0.675 | < 0.001 | < 0.001 | 0.001 | 0.917 |
CD3 (%) | 49 | 72.25 (7.01) | 72.02 (8.90) | 66.46 (12.67) | 73.07 (9.64) | 0.935 | 0.135 | 0.142 | 0.127 | 0.749 |
CD4 (%) | 49 | 48.66 (8.64) | 42.90 (11.72) | 41.01 (9.83) | 42.46 (8.21) | 0.122 | 0.032 | 0.619 | 0.670 | 0.905 |
CD8 (%) | 49 | 22.21 (9.32) | 29.02 (9.99) | 25.00 (6.75) | 29.82 (11.60) | 0.050 | 0.355 | 0.192 | 0.179 | 0.832 |
MC CD16+ (%) | 49 | 21.20 (7.57) | 23.79 (13.63) | 17.00 (9.07) | 18.00 (9.84) | 0.488 | 0.186 | 0.116 | 0.786 | 0.199 |
MC CD16− (%) | 49 | 78.87 (7.41) | 78.00 (12.01) | 83.93 (9.97) | 83.36 (10.64) | 0.809 | 0.131 | 0.147 | 0.885 | 0.199 |
CD3ζ (%)b | 49 | 77.58 (22.42) | 69.39 (40.75) | 64.86 (46.75) | 68.36 (43.75) | 0.382 | 0.291 | 0.699 | 0.773 | 0.913 |
NKCD56++ (%)b | 49 | 4.24 (3.74) | 4.63 (4.76) | 2.13 (2.31) | 3.18 (3.40) | 0.812 | 0.089 | 0.047 | 0.237 | 0.338 |
CD3ζNK (%)b | 49 | 94.20 (1.00) | 98.61 (0.00) | 81.12 (29.55) | 93.48 (14.75) | 0.330 | 0.174 | 0.053 | 0.169 | 0.061 |
Monocyte (%)b | 49 | 6.44 (2.38) | 6.626 (2.70) | 4.580 (3.55) | 8.76 (1.35) | 0.759 | 0.026 | 0.013 | 0.127 | 0.415 |