Table 1 Demographics, clinical characteristics, laboratory data, treatments, complications, and prognosis of DVT versus non-DVT patients with ARDS caused by bacterial pneumonia
From: Deep vein thrombosis in acute respiratory distress syndrome caused by bacterial pneumonia
Variables | Total (n = 90) | DVT (n = 40) | Non-DVT (n = 50) | P value |
|---|---|---|---|---|
Age (years) | 68 (57, 78) | 71 (60, 80) | 66 (51, 77) | 0.150 |
Male, n (%) | 69 (76.6) | 30 (75.0) | 39 (78.0) | 0.738 |
BMI | 23.8 ± 4.0 | 23.0 ± 3.9 | 24.4 ± 3.8 | 0.088 |
Bedridden time (days) | 10 (6, 18) | 9 (5, 19) | 11 (7, 18) | 0.603 |
CKD, n (%) | 6 (6.7) | 1 (2.5) | 5 (10.0) | 0.221 |
Wells score | 1 (1, 1) | 1 (1, 1) | 1 (1, 2) | 0.166 |
Padua prediction score | 6 (5, 6) | 6 (5, 6) | 5 (5, 6) | 0.481 |
Caprini score | 7 (6, 9) | 7 (5, 9) | 7 (6, 9) | 0.776 |
APACHE II score | 22 (19, 28) | 22 (18, 29) | 23 (19, 28) | 0.897 |
SIRS score | 15 (13, 16) | 15 (13, 17) | 14 (13, 15) | 0.016 |
 ≤ 15, n (%) | 60 (66.7) | 21 (52.5) | 39 (78.0) | 0.011a |
  > 15, n (%) | 30 (33.3) | 19 (47.5) | 11 (22.0) |  |
Coagulation function index | ||||
D-dimer (mg/L) | 2.0 (0.9, 4.7) | 2.8 (0.9, 6.1) | 1.9 (0.7, 2.8) | 0.035 |
PT (s) | 13.9 (12.1, 16.0) | 14.4 (12.2, 15.9) | 13.5 (11.9, 16.2) | 0.649 |
APTT (seconds) | 32.3 (29.2, 36.0) | 32.7 (29.0, 35.6) | 31.9 (29.3, 36.9) | 0.805 |
Scr (μmol/L) | 89.8 (66.0, 194.6) | 77.3 (56.4, 128.5) | 121.6 (71.4, 235.5) | 0.006 |
PAH, n (%) | 32 (38.6) | 15 (40.5) | 17 (37.0) | 0.739 |
PASP (mmHg)b | 45.2 ± 13.1 | 50.2 ± 13.0 | 40.8 ± 11.9 | 0.041 |
Treatments | ||||
CVC, n (%) | 35 (38.9) | 16 (40.0) | 19 (38.0) | 0.847 |
Sedative therapy, n (%) | 40 (44.4) | 23 (57.5) | 17 (34.0) | 0.026 |
CRRT, n (%) | 10 (11.1) | 3 (7.5) | 7 (14.0) | 0.502 |
HFNO, n (%) | 5(5.6) | 4(10.0) | 1(2.0) | 0.167 |
MV, n (%) | 68 (75.6) | 33 (82.5) | 35 (70.0) | 0.170 |
IMV, n (%) | 54 (60.0) | 32 (80.0) | 22 (44.4) | 0.001 |
Duration of IMV (days) | 3 (2, 6) | 4 (2, 6) | 3 (2, 7) | 0.927 |
NIV, n (%) | 37 (41.1) | 13 (32.5) | 24 (48.0) | 0.138 |
VTE prophylaxis, n (%) | 41 (45.6) | 17 (42.5) | 24 (48.0) | 0.603 |
LMWH, n (%) | 35 (38.9) | 14 (35.0) | 21 (42.0) | 0.498 |
LMWH + physical prophylaxis, n (%) | 26 (28.9) | 13 (32.5) | 13 (26.0) | 0.499 |
PaO2/FiO2 | 132 ± 60 | 122 ± 57 | 141 ± 61 | 0.141 |
Mild, n (%) | 16 (17.8) | 4 (10.0) | 12 (24.0) | 0.178a |
Moderate, n (%) | 40 (44.4) | 18 (45.0) | 22 (44.0) | Â |
Severe, n (%) | 34 (37.8) | 18 (45.0) | 16 (32.0) | Â |
Major complications | ||||
AKI, n (%) | 46 (51.1) | 17 (42.5) | 29 (58.0) | 0.144 |
ACI, n (%) | 39 (43.3) | 14 (35.0) | 25 (50.0) | 0.154 |
Coagulation dysfunction, n (%) | 82 (91.1) | 39 (97.5) | 43 (86.0) | 0.071 |
Septic shock, n (%) | 39 (43.3) | 18 (45.0) | 21 (42.0) | 0.775 |
ALI, n (%) | 43 (47.8) | 20 (50.0) | 23 (46.0) | 0.706 |
Number of US scan | 1 (1, 2) | 1 (1, 2) | 1 (1, 2) | 0.904 |
Duration to DVT or last negative US scan (days) | 5 (2, 12) | 5 (2, 10) | 5 (2, 13) | 0.797 |
Mortality, n (%) | 38 (42.2) | 18 (45.0) | 20 (40.0) | 0.633 |