|
Covariate
|
A. Risk factors for death
|
B. Risk factors for CLAD
|
C. Risk factors for Pseudomonas colonization
|
|---|
|
p value
|
HR
|
95% CI
|
p value
|
HR
|
95% CI
|
p value
|
HR
|
95% CI
|
|---|
|
Recipient age at LTX
|
0.013
|
1.04
|
1.01–1.08
|
0.022
|
1.04
|
1.01–1.08
|
0.544
|
1.01
|
0.98–1.05
|
|
Recipient sex (male vs female)
|
0.997
|
1.00
|
0.49–2.02
|
0.191
|
1.58
|
0.80–3.14
|
0.500
|
1.31
|
0.60–2.90
|
|
LTX procedure (bilateral vs single)
|
0.857
|
0.94
|
0.48–1.83
|
0.182
|
0.62
|
0.31–1.25
|
0.044
|
2.21
|
1.02–4.76
|
|
LTX indication (bronchiectasis vs others)
|
0.320
|
1.62
|
0.63–4.19
|
0.241
|
1.88
|
0.65–5.40
|
0.001
|
4.30
|
1.88–9.85
|
|
History of pre-transplant Pseudomonas
|
0.412
|
1.49
|
0.58–3.85
|
0.143
|
2.05
|
0.78–5.36
|
0.002
|
3.77
|
1.65–8.62
|
|
Chronic sinusitis
|
0.462
|
1.39
|
0.58–3.37
|
0.030
|
2.56
|
1.10–5.99
|
0.016
|
2.75
|
1.21–6.28
|
|
Ischemic time
|
0.999
|
1.00
|
0.99–1.01
|
0.320
|
0.999
|
0.99–1.01
|
0.933
|
1.00
|
0.99–1.01
|
|
Covariate
|
D. Risk factors for NTM colonization
|
E. Risk factors for Aspergillus colonization
|
|---|
|
p value
|
HR
|
95% CI
|
p value
|
HR
|
95% CI
|
|---|
|
Recipient age at LTX
|
0.241
|
1.03
|
0.98–1.08
|
0.432
|
1.02
|
0.98–1.06
|
|
Recipient sex (male vs female)
|
0.107
|
2.26
|
0.84–6.09
|
0.988
|
0.99
|
0.39–2.51
|
|
LTX procedure (bilateral vs single)
|
0.538
|
1.35
|
0.52–3.51
|
0.985
|
0.99
|
0.41–2.39
|
|
LTX indication (bronchiectasis vs others)
|
0.055
|
3.01
|
0.97–9.32
|
0.151
|
2.24
|
0.75–6.70
|
|
History of pre-transplant Pseudomonas
|
0.334
|
1.86
|
0.53–6.52
|
0.039
|
2.91
|
1.05–8.01
|
|
Chronic sinusitis
|
0.064
|
2.69
|
0.94–7.69
|
0.064
|
2.48
|
0.95–6.45
|
|
Ischemic time
|
0.576
|
1.00
|
0.99–1.01
|
0.800
|
1.00
|
0.99–1.01
|
- LTX, lung transplant; CLAD, chronic lung allograft dysfunction; CI, confidence interval; HR, hazard ratio; NTM, non-tuberculous mycobacterium
