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Table 1 Analysis of demographic and clinical characteristics of TDL patients stratified to the presence of postoperative complications

From: Incidence and risk factors of postoperative complications in patients with tuberculosis-destroyed lung

Variables

Total (n = 113%)

Non-complication group (n = 80%)

Complication group (n = 33%)

Crude OR (95% CI)

Adjusted OR (95% CI)

Sex

     

Male

51 (45.1)

31 (60.8)

20 (39.2)

2.432 (1.060–5.580)

 

Female

62 (54.9)

49 (79.0)

13 (21.0)

Ref

 

Age group (years)

     

 ≤ 65

110 (97.3)

79 (71.8)

31 (28.2)

Ref

 

 > 66

3 (2.7)

1 (33.3)

2 (66.7)

5.097 (0.446–58.250)

 

BMI (kg/m2)

     

 < 18.5

24 (21.2)

10 (41.7)

14 (58.3)

4.859 (1.834–12.875)

6.333 (1.957–20.500)

18.5–24.9

76 (67.3)

59 (77.6)

17 (22.4)

Ref

Ref

 ≥ 25

13 (11.5)

11 (84.6)

2 (15.4)

0.631 (0.127–3.126)

0.726 (0.120–4.381)

Smoking history

     

No

97 (85.8)

73 (75.3)

24 (24.7)

Ref

 

Yes

16 (14.2)

7 (43.8)

9 (56.2)

3.911 (1.315–11.633)

5.592 (1.519–21.334)

Smoking index

     

 < 400

4 (25.0)

2 (50.0)

2 (50.0)

Ref

 

 ≥ 400

12 (75.0)

5 (41.7)

7 (58.3)

1.4 (0.144–13.568)

 

Alcohol abuse

     

No

108 (95.6)

77 (71.3)

31 (28.7)

Ref

 

Yes

5 (4.4)

3 (60.0)

2 (40.0)

1.656 (0.264–10.397)

 

Comorbidities

     

No

91 (80.5)

67 (83.8)

24 (70.0)

Ref

 

Yes

22 (19.5)

13 (14.1)

9 (30.0)

1.933 (0.733–5.095)

 

Course of disease

     

 < 12 months

17 (15.0)

13 (76.5)

4 (23.5)

Ref

 

12–120 months

66 (58.4)

46 (70.0)

20 (30.0)

1.413 (0.410–4.871)

 

 > 120 months

30 (26.5)

21 (70.0)

9 (30.0)

1.393 (0.355–5.459)

 

Coinfection

     

No

80 (70.8)

64 (80.0)

16 (20.0)

Ref

Ref

Aspergillus or NTM

33 (29.2)

16 (46.7)

17 (53.3)

4.250 (1.771–10.198)

4.036 (1.385–11.766)

MDR

     

No

100 (88.5)

71 (71.0)

29 (29.0)

Ref

 

Yes

13 (11.5)

9 (69.2)

4 (30.8)

1.088 (0.310–3.815)

 

Severity of TDL

     

Lobe = 1

31 (27.4)

22

9

Ref

 

Lobe > 1

82 (72.6)

58

24

1.011 (0.407–2.512)

 

Lung function*

     

FVC%pred

 

65.6 ± 16.7

61.5 ± 19.2

0.986(0.957–1.015)

 

FEV1%pred

 

57.5 ± 18.3

55.9 ± 18.0

0.995(0.969–1.022)

 

MVV%pred

 

56.8 ± 19.8

55.6 ± 17.1

0.997(0.972–1.023)

 

DLCO%pred

 

59.5 ± 16.5

55.8 ± 8.7

1.018(0.995–1.042)

 
  1. Data are presented as mean (SD) or n (%) or median (range)
  2. Comorbidities include hypertension, diabetes and coronary heart disease. FEV1% pre, forced expiratory volume in one second as a percentage of predicted value; FVC % pre, forced vital capacity as a percentage of predicted value; MVV % pre, maximal voluntary ventilation as a percentage of predicted value; DLCO, lung diffusion capacity of predicted. In view of small sample size of patients with comorbidities, they are combined into one group for statistical analysis; * 23% (26/113) of the patients with massive hemoptysis underwent emergency surgery without preoperative pulmonary function examination, and 87 cases had pulmonary function examination results
  3. TDL tuberculosis destroyed lung, BMI body mass index, OR odds ratio, CI confidence interval, NTM nontuberculous mycobacteria, MDR multidrug resistance