Fig. 1From: Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD)Study flowchart. mMRC modified Medical Research Council Score, CRQ chronic respiratory questionnaire, HADS-A hospital anxiety depression score—anxiety, (S)AE (serious) adverse event. *Unless already performed in the 6 months before screeningBack to article page