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Table 5 Estimated changes in coagulation function and CRP in AECOPD patients associated with PM2.5

From: Effect of urban air pollution on CRP and coagulation: a study on inpatients with acute exacerbation of chronic obstructive pulmonary disease

Variable

PM2.5

The day of hospitalization

The day before hospitalization

Two day before hospitalization

< 25 mg/L

≥ 25 mg/L

t

p

< 25 mg/L

≥ 25 mg/L

t

p

< 25 mg/L

≥ 25 mg/L

t

p

n = 228

n = 89

n = 228

n = 89

n = 220

n = 97

D dimer

0.75 ± 1.06

0.70 ± 1.01

0.384

0.702

0.68 ± 1.01

0.73 ± 1.03

0.690

0.399

0.69 ± 0.89

0.72 ± 1.08

0.249

0.804

TT

16.39 ± 3.47

16.13 ± 2.49

0.763

0.446

16.39 ± 2.39

16.13 ± 2.94

0.731

0.465

16.31 ± 2.24

16.16 ± 3.02

0.433

0.665

PT

12.41 ± 2.29

12.29 ± 2.07

0.450

0.653

12.61 ± 2.76

12.03 ± 1.89

2.052

0.041

12.42 ± 2.59

12.28 ± 1.90

0.550

0.583

FIB

4.33 ± 3.20

4.39 ± 4.45

0.110

0.912

4.55 ± 4.85

4.31 ± 3.83

0.466

0.642

4.29 ± 4.60

4.41 ± 3.93

0.246

0.806

APTT

27.97 ± 4.44

28.40 ± 4.35

0.770

0.442

28.13 ± 4.27

28.34 ± 4.42

0.703

0.382

28.36 ± 4.48

28.24 ± 4.32

0.229

0.819

CRP

10.52 ± 11.94

10.42 ± 12.19

0.066

0.947

8.27 ± 11.84

11.30 ± 12.13

2.008

0.046

9.33 ± 12.21

10.89 ± 12.02

1.060

0.290

  1. PM2.5, Particulate matter smaller than 2.5 µm in diameter; TT, Thrombin Time; PT, Prothrombin Time; FIB, Fibrinogen; APTT, Activated Partial Thromboplastin Time; CRP,C-reactive protein
  2. p-values are shown for the Student’s t-tests