|
Variables
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
Hazard ratio
|
95% CI
|
P value
|
Hazard ratio
|
95% CI
|
P value
|
|---|
|
Age
|
1.120
|
1.085–1.157
|
< 0.001
|
1.138
|
1.092–1.186
|
< 0.001
|
|
Size
|
1.177
|
1.107–1.252
|
< 0.001
|
1.086
|
0.995–1.181
|
0.065
|
|
Lobulation
|
2.493
|
1.456–4.267
|
0.001
|
2.143
|
0.980–4.689
|
0.056
|
|
Spiculation
|
3.333
|
1.924–5.776
|
< 0.001
|
0.739
|
0.302–1.806
|
0.507
|
|
Pleural retraction sign
|
4.194
|
2.274–7.734
|
< 0.001
|
3.366
|
1.431–7.920
|
0.005
|
|
CT bronchus sign
|
3.529
|
2.064–6.035
|
< 0.001
|
2.608
|
1.190–5.714
|
0.017
|
|
Calcification
|
0.185
|
0.049–0.702
|
0.013
|
0.190
|
0.024–1.517
|
0.117
|
|
Mediastinal/hilar lymph nodule ≥ 10 mm
|
1.840
|
0.937–3.615
|
0.077
|
0.732
|
0.312–1.720
|
0.475
|
|
CEA
|
1.313
|
1.117–1.544
|
0.001
|
1.234
|
1.032–1.475
|
0.021
|
- CEA: Carcinoembryonic antigen; CI: confident interval; CT: computed tomography
