Table 1 GO BPs and KEGG pathways significantly related to 130 differential genes
From: DNA methylation and gene expression profiles to identify childhood atopic asthma associated genes
Category | Term | Count | PValue |
|---|---|---|---|
Biology process | GO:0006968 ~ cellular defense response | 5 | 1.06E−03 |
GO:0006952 ~ defense response | 13 | 1.90E−03 | |
GO:0055114 ~ oxidation reduction | 12 | 7.47E−03 | |
GO:0051494 ~ negative regulation of cytoskeleton organization | 4 | 7.79E−03 | |
GO:0002696 ~ positive regulation of leukocyte activation | 5 | 7.86E−03 | |
GO:0050867 ~ positive regulation of cell activation | 5 | 9.21E−03 | |
GO:0002703 ~ regulation of leukocyte mediated immunity | 4 | 1.03E−02 | |
GO:0019835 ~ cytolysis | 3 | 1.04E−02 | |
GO:0051129 ~ negative regulation of cellular component organization | 5 | 2.10E−02 | |
GO:0006922 ~ cleavage of lamin | 2 | 2.20E−02 | |
GO:0006923 ~ cleavage of cytoskeletal proteins during apoptosis | 2 | 2.20E−02 | |
GO:0010639 ~ negative regulation of organelle organization | 4 | 2.28E−02 | |
GO:0006865 ~ amino acid transport | 4 | 2.90E−02 | |
GO:0042330 ~ taxis | 5 | 3.08E−02 | |
GO:0006935 ~ chemotaxis | 5 | 3.08E−02 | |
GO:0016310 ~ phosphorylation | 12 | 3.39E−02 | |
GO:0002694 ~ regulation of leukocyte activation | 5 | 3.46E−02 | |
GO:0051251 ~ positive regulation of lymphocyte activation | 4 | 3.51E−02 | |
GO:0001562 ~ response to protozoan | 2 | 3.64E−02 | |
GO:0043242 ~ negative regulation of protein complex disassembly | 3 | 3.68E−02 | |
GO:0002697 ~ regulation of immune effector process | 4 | 3.88E−02 | |
GO:0050865 ~ regulation of cell activation | 5 | 4.07E−02 | |
GO:0001817 ~ regulation of cytokine production | 5 | 4.52E−02 | |
GO:0006690 ~ icosanoid metabolic process | 3 | 4.72E−02 | |
KEGG pathway | hsa04650:Natural killer cell mediated cytotoxicity | 5 | 3.59E−03 |
hsa00280:Valine, leucine and isoleucine degradation | 3 | 6.42E−03 | |
hsa00140:Steroid hormone biosynthesis | 3 | 6.95E−03 | |
hsa04080:Neuroactive ligand-receptor interaction | 6 | 9.17E−03 | |
hsa00590:Arachidonic acid metabolism | 3 | 9.75E−03 | |
hsa04514:Cell adhesion molecules (CAMs) | 4 | 1.28E−02 | |
hsa04612:Antigen processing and presentation | 3 | 1.84E−02 | |
hsa00240:Pyrimidine metabolism | 3 | 2.26E−02 | |
hsa00230:Purine metabolism | 3 | 4.26E−02 | |
hsa04060:Cytokine-cytokine receptor interaction | 4 | 4.53E−02 |