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Table 2 Clinical characteristics on admission

From: High neutrophils and low lymphocytes percentages in bronchoalveolar lavage fluid are prognostic factors of higher in-hospital mortality in diffuse alveolar hemorrhage

Variables All patients Survival Death p-value
Subject, n 68 50 18  
Respiratory conditions
Oxygen flow, L/min 3 (2–10) 3 (2–10) 5 (3–10) 0.12
Serological findings
White blood cell count, × 103 /μL 8.2 (6.6–10.5) 8.1 (6.6–10.4) 9.6 (6.4–10.5) 0.70
Neutrophils count, × 103 /μL (n = 66) 6.78 (4.53–8.65) 6.49 (4.49–8.80) 7.56 (5.37–8.54) 0.68
Lymphocytes, count, × 103 /μL (n = 66) 0.94 (0.69–1.25) 1.03 (0.76–1.25) 0.66 (0.43–1.35) 0.11
Hemoglobin, g/dL 10.8 (9.8–12.5) 10.7 (9.8–12.5) 11.2 (9.7–12.5) 0.95
Platelet count, × 103 /μL 198 (132–267) 206 (157–258) 179 (88.8–328) 0.68
LDH, IU/L 292 (243–379) 280 (238–363) 345 (269–388) 0.21
BUN, mg/dL 21.6 (16.1–32.7) 20.2 (15.9–30.6) 25.2 (18.5–34.9) 0.12
eGFR, mL/min 51.2 (40.8–67.8) 60.6 (43.4–71.9) 43.2 (29.8–50.9)  < 0.05
CRP, mg/dL 8.63 (3.82–13.5) 8.54 (3.48–13.2) 10.3 (7.77–14.2) 0.25
BALF findings
Total cell counts in BALF, × 104 /μL 5.2 (3.1–9.4) 5.1 (3.1–8.8) 5.4 (3.9–10.8) 0.79
Neutrophils percentage in BALF, % 32.0 (13.1–47.0) 23.5 (7.35–38.8) 58.8 (41.9–70.4)  < 0.05
Lymphocytes percentage in BALF, % 19.5 (8.9–39.9) 25.3 (13.0–50.6) 8.75 (6.1–12.8)  < 0.05
Clinical courses
Time from onset to admission, days 4 (2–7) 4 (2–9) 4 (2–5) 0.68
Time from admission to diagnosis of DAH, days 1 (0–3) 1 (0–3) 1 (0–3) 0.95
Treatments
Invasive ventilation, n 38 (56%) 22 (44%) 16 (89%)  < 0.05
Non-invasive ventilation, n 9 (13%) 8 (16%) 1 (5.6%) 0.23
Administration of antibiotics, n 57 (84%) 39 (78%) 18 (100%)  < 0.05
Administration of corticosteroids, n 56 (82%) 40 (80%) 16 (89%) 0.49
  1. Data presented as median (IQR) or absolute values (percentage)
  2. AT antithrombotic therapy, BALF bronchoalveolar lavage fluid, BUN blood urea nitrogen, Cr Creatinine, CRP C-reactive protein, DAH diffuse alveolar hemorrhage, eGFR estimated glomerular filtration rate, IQR interquartile range, LDH lactate dehydrogenase