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Table 2 Clinical characteristics on admission

From: High neutrophils and low lymphocytes percentages in bronchoalveolar lavage fluid are prognostic factors of higher in-hospital mortality in diffuse alveolar hemorrhage

Variables

All patients

Survival

Death

p-value

Subject, n

68

50

18

 

Respiratory conditions

Oxygen flow, L/min

3 (2–10)

3 (2–10)

5 (3–10)

0.12

Serological findings

White blood cell count, × 103 /μL

8.2 (6.6–10.5)

8.1 (6.6–10.4)

9.6 (6.4–10.5)

0.70

Neutrophils count, × 103 /μL (n = 66)

6.78 (4.53–8.65)

6.49 (4.49–8.80)

7.56 (5.37–8.54)

0.68

Lymphocytes, count, × 103 /μL (n = 66)

0.94 (0.69–1.25)

1.03 (0.76–1.25)

0.66 (0.43–1.35)

0.11

Hemoglobin, g/dL

10.8 (9.8–12.5)

10.7 (9.8–12.5)

11.2 (9.7–12.5)

0.95

Platelet count, × 103 /μL

198 (132–267)

206 (157–258)

179 (88.8–328)

0.68

LDH, IU/L

292 (243–379)

280 (238–363)

345 (269–388)

0.21

BUN, mg/dL

21.6 (16.1–32.7)

20.2 (15.9–30.6)

25.2 (18.5–34.9)

0.12

eGFR, mL/min

51.2 (40.8–67.8)

60.6 (43.4–71.9)

43.2 (29.8–50.9)

 < 0.05

CRP, mg/dL

8.63 (3.82–13.5)

8.54 (3.48–13.2)

10.3 (7.77–14.2)

0.25

BALF findings

Total cell counts in BALF, × 104 /μL

5.2 (3.1–9.4)

5.1 (3.1–8.8)

5.4 (3.9–10.8)

0.79

Neutrophils percentage in BALF, %

32.0 (13.1–47.0)

23.5 (7.35–38.8)

58.8 (41.9–70.4)

 < 0.05

Lymphocytes percentage in BALF, %

19.5 (8.9–39.9)

25.3 (13.0–50.6)

8.75 (6.1–12.8)

 < 0.05

Clinical courses

Time from onset to admission, days

4 (2–7)

4 (2–9)

4 (2–5)

0.68

Time from admission to diagnosis of DAH, days

1 (0–3)

1 (0–3)

1 (0–3)

0.95

Treatments

Invasive ventilation, n

38 (56%)

22 (44%)

16 (89%)

 < 0.05

Non-invasive ventilation, n

9 (13%)

8 (16%)

1 (5.6%)

0.23

Administration of antibiotics, n

57 (84%)

39 (78%)

18 (100%)

 < 0.05

Administration of corticosteroids, n

56 (82%)

40 (80%)

16 (89%)

0.49

  1. Data presented as median (IQR) or absolute values (percentage)
  2. AT antithrombotic therapy, BALF bronchoalveolar lavage fluid, BUN blood urea nitrogen, Cr Creatinine, CRP C-reactive protein, DAH diffuse alveolar hemorrhage, eGFR estimated glomerular filtration rate, IQR interquartile range, LDH lactate dehydrogenase