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Table 3 Comparison of the CPET parameters of CTEPH subjects of different severity

From: Cardiopulmonary exercise testing and pulmonary function testing for predicting the severity of CTEPH

Variables Mild Moderate Severe P
OUES (L/min/log(L/min)) 1.3 ± 0.4 1.0 ± 0.3 1.0 ± 0.4 0.066
OUEP (mL/L) 23.4 (21.0, 27.9) 22.7 (21.4, 23.8) 21.3 (19.1, 22.7) 0.077
VE/VCO2 slope 40.9 (32.3, 53.0) 48.4 (41.1, 68.7) 61.7 (49.9, 78.5) 0.005
LOWEST VE/VCO2 43.7 ± 9.1 48.6 ± 5.8 55.0 ± 10.1 0.008
  1. Range for “Mild”: 35 > PAP (mm Hg) ≥ 25; range for “Moderate”: 45 > PAP (mm Hg) ≥ 35; range for “Severe”: PAP (mm Hg) ≥ 45. The data are presented as mean ± SD or median (interquartile range). Statistical analysis of characteristics of “Mild”, “Moderate” and “Severe” was analyzed with One-way ANOVA test or Kruskal–Wallis test, and was presented as “P”. OUES = oxygen uptake efficiency slope; OUEP = oxygen uptake efficiency plateau; VE = ventilation; VCO2 = carbon dioxide output