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Table 5 Predictive value of single factor and multiple factors for severe CTEPH

From: Cardiopulmonary exercise testing and pulmonary function testing for predicting the severity of CTEPH

Variables

AUC

95% CI

P

Cutoff-point value

Sensitivity

Specificity

Youden index

VE @ AT (L/min)

0.769

0.630–0.908

0.001

29.5

65.7%

85.0%

0.507

VO2 @ Peak (mL/kg/min)

0.740

0.606–0.874

0.003

13.0

50.0%

91.4%

0.414

Logit(P)

0.843

0.732–0.954

0.000

0.716

68.6%

90.0%

0.586

  1. Range for “Severe”: PAP (mm Hg) ≥ 45. AUC = area under ROC curve; CI = confidence interval; VE = minute ventilation; VO2 = oxygen uptake