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Table 5 Predictive value of single factor and multiple factors for severe CTEPH

From: Cardiopulmonary exercise testing and pulmonary function testing for predicting the severity of CTEPH

Variables AUC 95% CI P Cutoff-point value Sensitivity Specificity Youden index
VE @ AT (L/min) 0.769 0.630–0.908 0.001 29.5 65.7% 85.0% 0.507
VO2 @ Peak (mL/kg/min) 0.740 0.606–0.874 0.003 13.0 50.0% 91.4% 0.414
Logit(P) 0.843 0.732–0.954 0.000 0.716 68.6% 90.0% 0.586
  1. Range for “Severe”: PAP (mm Hg) ≥ 45. AUC = area under ROC curve; CI = confidence interval; VE = minute ventilation; VO2 = oxygen uptake