Fig. 3
From: Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?
Alpha diversity as measured by the Shannon index, stratified by disease, sampling modality and whether subjects received antibiotics between the two procedures. The samples from the first bronchoscopy are connected by continuous lines, whereas the second bronchoscopy samples are connected by a dotted line. Samples of individuals that received antibiotics between the two procedures are coloured blue, subjects that did not receive antibiotics beween procedures are colored red. S0: control subjects, S1: COPD, FEV1 > 50% of predicted, S2: COPD, FEV1 < 50% of predicted. OW: oral wash. PBAL1: First fraction of protected broncho-alveolar lavage. PBAL2: second fraction of protected broncho-alveolar lavage. rPSB: protected specimen brush from right lower lobe