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Table 1 Characteristics of participants examined two times by bronchoscopy in the MicroCOPD study

From: Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?

 

COPD

Controls

Asthma

Comparison of COPD versus control

N

38

21

1

 

Men, N (%)

24 (68%)

14 (67%)

1

p > 0.05*

Age at exam 1, years, median (IQR)

69.3 (9.1)

67.8 (7.0)

55.2

p > 0.05***

Never smoker, N (%)

0

1 (5%)

0

p > 0.05*

Current smoker, N (%)

9 (24%)

7 (33%)

0

 

Ex-smoker, N (%)

29 (76%)

13 (62%)

1

 

Pack years, median (IQR)

30 (22)

24 (16..8)

38

p > 0.05***

FEV1, % predicted (SD)

55.6 (28.2)

100.1 (14.6)

102.3

p < 0.001***

ICS use, N (%)

26 (68%)

1 (5%)

0

p < 0.001*

Antibiotic use between exams 1 and 2, N (%)

10 (26.3)

4 (19.1)

0

p > 0.05*

Median number of days between exam 1 and 2 (IQR)

139.5 (75)

156 (33)

298

p > 0.05***

  1. IQR interquartile range, FEV1 forced expiratory volume in 1 s, ICS inhaled corticosteroids, COPD chronic obstructive pulmonary disease
  2. *Chi-square test
  3. **t-test
  4. ***Wilcoxon rank-sum test