From: Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?
COPD | Controls | Asthma | Comparison of COPD versus control | |
---|---|---|---|---|
N | 38 | 21 | 1 | |
Men, N (%) | 24 (68%) | 14 (67%) | 1 | p > 0.05* |
Age at exam 1, years, median (IQR) | 69.3 (9.1) | 67.8 (7.0) | 55.2 | p > 0.05*** |
Never smoker, N (%) | 0 | 1 (5%) | 0 | p > 0.05* |
Current smoker, N (%) | 9 (24%) | 7 (33%) | 0 | |
Ex-smoker, N (%) | 29 (76%) | 13 (62%) | 1 | |
Pack years, median (IQR) | 30 (22) | 24 (16..8) | 38 | p > 0.05*** |
FEV1, % predicted (SD) | 55.6 (28.2) | 100.1 (14.6) | 102.3 | p < 0.001*** |
ICS use, N (%) | 26 (68%) | 1 (5%) | 0 | p < 0.001* |
Antibiotic use between exams 1 and 2, N (%) | 10 (26.3) | 4 (19.1) | 0 | p > 0.05* |
Median number of days between exam 1 and 2 (IQR) | 139.5 (75) | 156 (33) | 298 | p > 0.05*** |