Table 2 Univariable analysis of potential risk factors for severe restenosis after therapeutic bronchoscopy
Variables | Severe restenosis | P value | |
|---|---|---|---|
No (n = 141) | Yes (n = 92) | ||
Age (y), (mean ± SD) | 65.9 ± 8.7 | 67.6 ± 7.3 | 0.123 |
Gender, n (%) | |||
Male | 126 (89.4) | 88 (95.7) | 0.086 |
Female | 15 (10.6) | 4 (4.3) | |
Diabetes, n (%) | |||
Yes | 7 (5.0) | 4 (4.3) | 0.828 |
No | 134 (95.0) | 88 (95.7) | |
Hypertension, n (%) | |||
Yes | 39 (27.7) | 19 (20.7) | 0.227 |
No | 102 (72.3) | 73 (79.3) | |
COPD, n (%) | |||
Yes | 13 (9.2) | 8 (8.7) | 0.891 |
No | 128 (90.8) | 84 (91.3) | |
Dyspnea index, n (%) | 0.618 | ||
0 | 26 (18.4) | 16 (17.4) | |
1 | 5 (3.5) | 4 (4.3) | |
2 | 16 (11.3) | 11 (12.0) | |
3 | 22 (15.6) | 8 (8.7) | |
4 | 72 (51.1) | 53 (57.6) | |
Initial degree of MCAS, (mean ± SD, %) | 72.3 ± 25.0 | 83.9 ± 20.4 | < 0.001 |
Post-intervention residual stenosis, (mean ± SD, %) | 26.1 ± 17.8 | 31.8 ± 15.9 | 0.012 |
Location of the lesion, n (%) | < 0.001 | ||
Trachea | 31 (22.0) | 3 (3.3) | |
Left main bronchus | 39 (27.7) | 36 (39.1) | |
Right main bronchus | 41 (29.1) | 37 (40.2) | |
Right intermediate bronchus | 30 (21.3) | 16 (17.4) | |
Histological types, n (%) | 0.463 | ||
Lung adenocarcinoma | 4 (2.8) | 1 (1.1) | |
Lung squamous cell carcinoma | 108 (76.6) | 78 (84.8) | |
SCLC | 12 (8.5) | 5 (5.4) | |
Other* | 17 (12.1) | 8 (8.7) | |
Other treatments after intervention,** n (%) | 0.366 | ||
0 | 34 (24.1) | 16 (17.4) | |
1 | 45 (31.9) | 36 (39.1) | |
≥ 2 | 62 (44.0) | 40 (43.5) | |