Table 2 Multivariable logistic regression of independent factors associated with the risk of ICU admission, mortality, and duration of hospitalization
From: Assessment of the HScore as a predictor of disease outcome in patients with COVID-19
Variables | Crude effect measure (95% CI) | P value | Adjusted effect measure (95% CI) | P value |
|---|---|---|---|---|
Crude OR (95% CI) | Adjusted OR (95% CI) | |||
ICU admission (as outcome) | ||||
HScore | ||||
Moderate | 2.95 (1.35–6.44) | 0.007 | 4.58 (1.78–11.79) | 0.002 |
High | 3.4 (1.40–8.22) | 0.007 | 4.93 (1.50–16.17) | 0.008 |
Overweight | 0.39 (0.20–o.75) | 0.005 | 0.35 (0.14–0.82) | 0.017 |
Diastolic Blood pressure | 0.95 (0.93–0.98) | 0.002 | 0.96 (0.92–0.99) | 0.046 |
Loss of appetite | 0.11 (0.01–0.9) | 0.040 | 0.20 (0.001–0.25) | 0.002 |
Fatigue | 1.04 (0.50–2.19) | 0.899 | 5.25 (1.67–16.48) | 0.004 |
Lymphocyte | 0.91 (0.87–0.95) | < 0.001 | 0.90 (0.86–0.94) | < 0.001 |
Hemoglobin | 0.81 (0.70–0.93) | 0.003 | 0.73 (0.60–0.88) | 0.001 |
Age | 0.99 (0.98, 1.00) | 0.187 | 0.99 (0.97, 1.01) | 0.399 |
Gender (Ref.: female) | 0.86 (0.46, 1.63) | 0.649 | 0.48 (0.20, 1.14) | 0.097 |
Mortality (as outcome) | ||||
HScore | 1.02 (1.01–1.03) | < 0.001 | 1.02 (1.00–1.04) | 0.009 |
ICU admission | 25.5 (3.1–209.2) | 0.003 | 66.06 (3.8–1160.5) | 0.004 |
Systolic Blood pressure | 0.94 (0.91–0.98) | 0.006 | 0.93 (0.88–0.98) | 0.009 |
Potassium | 0.19 (0.05–0.72) | 0.015 | 0.11 (0.02–0.63) | 0.013 |
Age | 0.98 (0.95, 1.00) | 0.098 | 1.06 (0.99, 1.12) | 0.083 |
Gender (Ref.: female) | 0.47 (0.11, 1.92) | 0.294 | 0.49 (0.06, 3.87) | 0.497 |
Variables | Crude effect measure (95% CI) | P value | Adjusted effect measure (95% CI) | P value |
|---|---|---|---|---|
Crude HR (95% CI) | Adjusted HR (95% CI) | |||
Discharge from hospital (as outcome) | ||||
HScore* | ||||
Moderate | 0.61 (0.39–0.94) | 0.024 | 0.60 (0.37–0.97) | 0.036 |
High | 0.41 (0.24–0.69) | 0.001 | 0.42 (0.22–0.78) | 0.007 |
Cardiovascular disease | 0.67 (0.38–1.21) | 0.185 | 0.40 (0.21- 0.78) | 0.007 |
Respiratory disease | 4.24 (2.02–8.90) | < 0.001 | 5.47 (2.39–12.52) | < 0.001 |
Chronic kidney disease | 0.52 (0.13–2.14) | 0.362 | 11.09 (1.38–89.10) | 0.024 |
Respiratory status | 1.40 (1.09–1.81) | 0.009 | 1.34 (1.03–1.74) | 0.027 |
Oxygen therapy | 0.43 (0.25–0.73) | 0.002 | 0.22 (0.11- 0.45) | < 0.001 |
Pneumonia | 5.26 (2.53–10.94) | < 0.001 | 4.56 (1.99–10.46) | < 0.001 |
Septic shock | 0.42 (0.20–0.87) | 0.020 | 0.12 (0.04–0.34) | < 0.001 |
White blood cell counts | 0.999 (0.993–1.004) | 0.719 | 1.006 (1.00–1.01) | 0.042 |
Red blood cell counts | 1.82 (1.40–2,36) | < 0.001 | 1.59 (1.16–2.18) | 0.004 |
Lymphocyte | 1.03 (1.02–1.04) | < 0.001 | 1.03 (1.01–1.04) | 0.001 |
Aspartate aminotransferase | 0.996 (0.991–1.001) | 0.178 | 1.006 (1.00–1.01) | 0.023 |
Alanine aminotransferase | 0.995 (0.989–1.001) | 0.178 | 0.98 (0.97–0.99) | 0.011 |
Phosphorus | 0.83 (0.74–0.93) | 0.002 | 0.82 (0.69–0.98) | 0.027 |
Age | 0.99 (0.98, 1.00) | 0.110 | 0.99 (0.98, 1.00) | 0.419 |
Gender (Ref.: female) | 0.79 (0.54, 1.15) | 0.217 | 1.13 (0.73, 1.74) | 0.584 |