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Table 1 Characteristics of patients with MRSA pneumonia and patients with non-MRSA pneumonia after 1:4 matching

From: In-hospital mortality associated with community-acquired pneumonia due to methicillin-resistant Staphylococcus aureus: a matched-pair cohort study

  MRSA pneumonia Non-MRSA pneumonia p-value
n (%) n (%)
Sex      0.943
 Male 2059 (66.4) 8186 (66.4)  
 Female 1043 (33.6) 4134 (33.6)  
Age (years, mean ± SD) 79.6 ± 10.7 79.5 ± 10.5 0.698
Body mass index (kg/m2)       < 0.001
 < 18.5 1388 (44.7) 3539 (28.7)  
 18.5–24.9 1136 (36.6) 5899 (47.9)  
 25–29.9 116 (3.7) 1147 (9.3)  
 ≥ 30 28 (0.9) 199 (1.6)  
 Missing 434 (14.0) 1536 (12.5)  
ADL score (Barthel Index)       < 0.001
 85–100 474 (15.3) 4144 (33.4)  
 60–80 159 (5.1) 991 (8.0)  
 0–55 2024 (65.2) 5503 (44.7)  
 Missing 445 (14.3) 1712 (13.9)  
Smoking history      0.003
 Yes 1226 (39.5) 5239 (42.5)  
 No 1876 (60.5) 7086 (57.5)  
Hugh-Jones grade       < 0.001
 I 132 (4.3) 1604 (13.0)  
 II 193 (6.2) 1774 (14.4)  
 III 231 (7.5) 1411 (11.5)  
 IV 435 (14.0) 2444 (19.8)  
 V 948 (30.6) 2375 (19.3)  
 Missing 1163 (37.5) 2712 (22.0)  
A-DROP score       < 0.001
 0 162 (5.2) 1089 (8.8)  
 1 639 (20.6) 3882 (31.5)  
 2 870 (28.0) 3871 (31.4)  
 3 701 (22.6) 2099 (17.0)  
 4 410 (13.2) 791 (6.4)  
 5 218 (7.0) 316 (2.6)  
 Missing 102 (3.3) 272 (2.2)  
Dehydration       < 0.001
 Yes 1788 (55.6) 5443 (44.2)  
 No 1288 (41.5) 6779 (55.0)  
 Missing 26 (0.8) 98 (0.8)  
Respiratory failure       < 0.001
 Yes 1612 (52.0) 4591 (37.3)  
 No 1468 (47.3) 7642 (62.0)  
 Missing 22 (0.7) 87 (0.7)  
Orientation disturbance       < 0.001
 Yes 941 (30.3) 1934 (15.7)  
 No 2100 (67.7) 10,285 (83.5)  
 Missing 61 (2.0) 101 (0.8)  
Systolic blood pressure       < 0.001
 < 90 mmHg 502 (16.2) 1013 (8.2)  
 ≥ 90 mmHg 2581 (83.2) 11,243 (91.3)  
 Missing 19 (0.6) 64 (0.5)  
CRP ≥ 20 mg/mL or infiltration covering at least two-thirds of one lung on chest radiography       < 0.001
 Yes 477 (15.4) 1369 (11.1)  
 No 1030 (33.2) 5185 (42.1)  
 Missing 1595 (51.4) 5766 (46.8)  
Mechanical ventilation at admission       < 0.001
 Yes 263 (8.5) 408 (3.3)  
 No 2839 (91.5) 11,912 (96.7)  
ICU admission       < 0.001
 Yes 101 (3.3) 157 (1.3)  
 No 3001 (96.7) 12,163 (98.7)  
Haemodialysis       < 0.001
 Yes 115 (3.7) 216 (1.8)  
 No 2987 (96.3) 12,104 (98.2)  
Emergency transport       < 0.001
 Yes 1061 (34.2) 3524 (28.6)  
 No 2401 (65.8) 8796 (71.4)  
COPD      0.003
 Yes 328 (10.6) 1548 (12.6)  
 No 2774 (89.4) 10,772 (87.4)  
Interstitial lung disease      0.231
 Yes 88 (2.8) 404 (3.3)  
 No 3014 (97.2) 11,916 (96.7)  
Aspiration pneumonia       < 0.001
 Yes 229 (7.4) 206 (1.7)  
 No 2873 (92.6) 12,114 (98.3)  
Pseudomonas aeruginosa      0.635
Pneumonia
 Yes 67 (2.2) 287 (2.3)  
 No 3035 (97.8) 12,033 (97.7)  
Diabetes      0.999
 Yes 571 (18.4) 2268 (18.4)  
 No 2531 (81.6) 10,052 (81.6)  
  1. MRSA, methicillin-resistant Staphylococcus aureus; ADL, activities of daily living; A-DROP, Age, Dehydration, Respiratory Failure, Orientation Disturbance and Blood Pressure; CRP, C-reactive protein; ICU, intensive care unit; COPD; chronic obstructive pulmonary disease