|
Sub-groups
|
sHR (95% confidence interval)
|
P value
|
|---|
|
PaO2/FiO2 ratio
| | |
|
> 100 mm Hg
|
3.44 (2.04–5.78)
|
< 0.001
|
|
≤ 100 mm Hg
|
2.17 (1.07–4.41)
|
0.03
|
|
Serum ferritin level
| | |
|
< 1000 mcg/L
|
3.45 (1.87–6.38)
|
< 0.001
|
|
≥ 1000 mcg/L
|
2.79 (1.52–5.11)
|
0.001
|
|
Time from ICU admission to IVIG therapy
| | |
|
< 5 days
|
2.65 (1.07–6.56)
|
0.035
|
|
≥ 5 days
|
3.89 (1.85–8.18)
|
< 0.001
|
|
Number of IVIG doses received
| | |
|
≤ 3 doses
|
3.72 (1.39–9.91)
|
0.009
|
|
> 3 doses
|
3.42 (1.69–6.93)
|
0.001
|
- IVIG, intravenous immunoglobulin; sHR, sub-distribution hazard ratio; PaO2/FiO2 ratio, ratio of partial pressure arterial oxygen and fraction of inspired oxygen; mcg/L, microgram per liter
