Univariate Cox regression | Multivariate Cox regression | |||||
---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |
Age | 1.054 | 1.003, 1.107 | 0.039 | 1.070 | 1.008, 1.135 | 0.026 |
Male | 1.534 | 0.688, 3.420 | 0.296 | − | ||
Current/ex-smoker | 2.094 | 0.871, 5.033 | 0.099 | − | ||
BMI | 0.999 | 0.872, 1.144 | 0.985 | − | ||
HRCT pattern | − | |||||
UIP | 1.000 | Reference | ||||
Probable UIP | 0.559 | 0.201, 1.554 | 0.265 | |||
Indeterminate for UIP | 0.295 | 0.080, 1.083 | 0.066 | |||
CT sign | ||||||
Emphysema | 1.513 | 0.559, 4.092 | 0.415 | − | ||
Anterior upper lobe honeycomb-like lesion | 2.751 | 1.151, 6.575 | 0.023 | 3.354 | 1.304, 8.629 | 0.012 |
Increased attenuation around honeycomb or traction bronchiectasis | 1.038 | 0.468, 2.301 | 0.927 | − | ||
Honeycomb | 2.175 | 0.881, 5.37 | 0.092 | − | ||
Concomitant with MPA (MPA-ILD) | 1.056 | 0.463, 2.408 | 0.897 | − | ||
Acute exacerbation of ILD | 1.329 | 0.524, 3.368 | 0.549 | − | ||
Diffuse pulmonary hemorrhage | 11.363 | 3.619, 35.67 | < 0.001 | 9.822 | 2.977, 32.406 | < 0.001 |
CRP | 1.196 | 1.051, 1.363 | 0.007 | 1.250 | 1.081, 1.444 | 0.003 |
%FVC | 0.986 | 0.956, 1.017 | 0.381 | − | ||
%DLCO | 0.990 | 0.962, 1.020 | 0.526 | − | ||
Anti-inflammatory agent | 0.952 | 0.425, 2.129 | 0.904 | − | ||
Anti-fibrotic agent | 0.629 | 0.146, 2.704 | 0.533 | − |