Table 2 Performance of HT-NGS and conventional microbiological testing in the diagnosis of pulmonary infection in lung transplant recipients
| Â | Â | Infection (35) | Non-infection (16) | Sensitivity% (95%CI) | Specificity% (95%CI) | PPV% (95%CI) | NPV% (95%CI) |
|---|---|---|---|---|---|---|---|
HT-NGS | + | 34 | 11 | 97.14 (83.38–99.85) | 31.25 (12.13–58.52) | 75.56 (60.14–86.61) | 83.33 (36.48–99.12) |
|  | − | 1 | 5 |  |  |  |  |
Conventional microbiological testing | + | 24 | 6 | 68.57 (50.58–82.57) | 62.50 (35.87–83.72) | 80.00 (60.87–91.60) | 47.62 (26.39–69.66) |
|  | − | 11 | 10 |  |  |  |  |