Parameter | BPT (+) | BPT (−) | ||||
---|---|---|---|---|---|---|
SP sign (+) (N = 341) | SP sign (−) (N = 5101) | P value | SP sign (+) (N = 1782) | SP sign (−) (N = 6437) | P value | |
Age, years | 37 (24, 52) | 21 (8, 48) | < .0001 | 39 (30, 51) | 40 (30, 53) | .173 |
Sex, n (%) | < .0001 | < .0001 | ||||
Male | 121 (35%) | 2618 (51%) | 714 (40%) | 3162 (49%) | ||
Female | 220 (65%) | 2483 (49%) | 1068 (60%) | 3275 (51%) | ||
BMI, kg/m2 | 22.3 (19.6, 24.9) | 20.1 (16.0, 23.6) | < .0001 | 22.6 (20.4, 24.8) | 22.6 (20.1, 25.0) | .337 |
Obesity, n (%) (BMI ≥ 30 kg/m2) | 13/341 (4%) | 114/5101 (2%) | .062 | 54/1782 (3%) | 90/6437 (1%) | < .0001 |
FVC % predicted, % | 102.4 (94.9, 112.0) | 98.8 (90.9, 107.3) | < .0001 | 103.0 (94.9, 112.0) | 100.0 (91.0, 100.6) | < .0001 |
FEV1% predicted, % | 97.5 (88.2, 105.8) | 91.9 (82.1, 101.1) | < .0001 | 101.0 (93.4, 109.2) | 97.0 (88.2, 106.0) | < .0001 |
FEV1/FVC ratio | 0.80 (0.75, 0.84) | 0.79 (0.72, 0.85) | .009 | 0.83 (0.79, 0.87) | 0.81 (0.77, 0.86) | < .0001 |
PEF % predicted, % | 95.5 (85.6, 105.5) | 92.0 (81.4, 103.6) | < .0001 | 103.8 (93.0, 114.7) | 103.6 (92.5, 115.2) | .824 |
FEF50% % predicted, % | 74.6 (60.2, 88.7) | 63.1 (49.0, 80.0) | < .0001 | 86.3 (71.8, 103.3) | 79.0 (63.2, 95.6) | < .0001 |
FEF75% % predicted, % | 55.8 (40.7, 71.0) | 49.5 (35.6, 67.6) | < .0001 | 65.0 (50.7, 84.4) | 62.0 (46.4, 82.1) | < .0001 |
MMEF % predicted, % | 65.8 (52.6, 81.4) | 59.2 (44.2, 76.8) | < .0001 | 77.5 (64.1, 92.4) | 72.7 (57.5, 88.7) | < .0001 |