Table 3 PFT values of patients with pre-BDTs
Parameter | BDT (+) | BDT (−) | ||||
|---|---|---|---|---|---|---|
SP sign (+) (N = 25) | SP sign (−) (N = 2904) | P value | SP sign (+) (N = 194) | SP sign (−) (N = 5044) | P value | |
Age, years | 35 (29, 57) | 57.5 (45, 66) | < .0001 | 55 (45, 63) | 62 (52, 69) | < .0001 |
Sex, n (%) | .014 | < .0001 | ||||
Male | 12 (48%) | 2047 (70%) | 105 (54%) | 3554 (70%) | ||
Female | 13 (52%) | 857 (30%) | 89 (46%) | 1490 (30%) | ||
BMI, kg/m2 | 22.5 (19.9, 24.2) | 22.5 (19.8, 25) | .795 | 23.7 (21.4, 26.0) | 22.2 (19.5, 24.8) | < .0001 |
Obesity, n (%) (BMI ≥ 30 kg/m2) | 0/25 (0%) | 96 (3%) | 1.000 | 7/194 (4%) | 127 (3%) | .347 |
FVC % predicted, % | 92.8 (82.9, 100.5) | 78.1 (65.1, 91.0) | < .0001 | 101.1 (88.5, 112.5) | 80.0 (66.8, 94.4) | < .0001 |
FEV1% predicted, % | 72.1 (63.9, 78.5) | 51.0 (35.9, 64.6) | < .0001 | 88.4 (78.5, 97.0) | 58.0 (40.0, 74.0) | < .0001 |
FEV1/FVC ratio | 0.67 (0.62, 0.71) | 0.52 (0.42, 0.63) | < .0001 | 0.73 (0.68, 0.77) | 0.59 (0.44, 0.69) | < .0001 |
PEF % predicted, % | 76.1 (69.5, 84.4) | 52.6 (36.8, 69.4) | < .0001 | 90.9 (78.5, 102.7) | 62.1 (42.0, 82.5) | < .0001 |
FEF50% % predicted, % | 38.5 (27.0, 47.3) | 18.0 (10.3, 30.2) | < .0001 | 52.9 (42.9, 67.1) | 23.8 (11.9, 40.8) | < .0001 |
FEF75% % predicted, % | 24.2 (18.5, 33.5) | 15.5 (10.8, 23.0) | < .0001 | 31.3 (23.1, 43.0) | 19.4 (12.6, 29.7) | < .0001 |
MMEF % predicted, % | 30.9 (21.1, 40.6) | 15.8 (9.7, 25.2) | < .0001 | 44.2 (34.4, 53.6) | 20.5 (11.3, 34.9) | < .0001 |