|
Age (years)
|
58.5 (49.0–66.0)
|
58.0 (50.0–66.0)
|
59.0 (48.0–66.0)
|
|
Male, no. (%)
|
426 (54.1)
|
204 (52.4)
|
222 (56.1)
|
|
Body mass index (kg/m2)
|
23.7 (21.1–26.0)
|
23.7 (21.3–26.0)
|
23.6 (21.0–26.1)
|
|
Current smoker, no. (%)
|
173 (22.0)
|
85 (21.7)
|
88 (22.2)
|
|
Pack-years no
|
30.0 (15.0–45.0)
|
30.0 (13.5–50.0)
|
30.0 (15.0–40.0)
|
|
Indication for bronchoscopy, no. (%)
| | | |
|
Hemoptysis
|
87 (11.0)
|
40 (10.2)
|
47 (11.9)
|
|
Unexplained chronic cough
|
39 (4.9)
|
22 (5.6)
|
17 (4.3)
|
|
Non-resolving pneumonia
|
165 (20.9)
|
78 (19.9)
|
87 (22.0)
|
|
Pneumonia in immunocompromised host
|
71 (9.0)
|
41 (10.5)
|
30 (7.6)
|
|
Interstitial lung disease
|
158 (20.1)
|
85 (21.7)
|
73 (18.4)
|
|
Suspected lung cancer
|
260 (33.0)
|
123 (31.4)
|
137 (34.6)
|
|
Foreign body aspiration
|
8 (1.0)
|
3 (0.8)
|
5 (1.3)
|
|
Vital signs
| | | |
|
Temperature, °C
|
36.6 ± 0.51
|
36.6 ± 0.49
|
36.6 ± 0.53
|
|
Respiratory rate (beats/min)
|
17 ± 4
|
17 ± 5
|
18 ± 4
|
|
Heart rate (beats/min)
|
84 ± 15
|
84 ± 15
|
83 ± 15
|
|
Mean arterial pressure (mmHg)
|
93 ± 17
|
93 ± 20
|
94 ± 13
|
|
Arterial blood gas (room air)
| | | |
|
pH
|
7.42 (7.40–7.44)
|
7.42 (7.40–7.44)
|
7.42 (7.39–7.44)
|
|
PaO2 (mmHg)
|
79.0 (71.0–88.0)
|
80.0 (70.0–89.0)
|
79.0 (71.0–88.0)
|
|
PaCO2 (mmHg)
|
40.0 (37.0–43.0)
|
40.0 (37.0–43.0)
|
40.0 (37.0–43.0)
|
|
HCO3− (mmol/L)
|
24.4 (21.8–27.2)
|
24.6 (22.2–26.9)
|
23.8 (21.4–27.9)
|
|
SaO2 (%)
|
96.0 (94.0–97.0)
|
96.0 (94.0–97.0)
|
96.0 (94.0–97.0)
|
|
Baseline spirometry
| | | |
|
FVC (L)
|
3.08 ± 0.95
|
3.13 ± 0.91
|
3.03 ± 0.98
|
|
FEV1 (L)
|
2.32 ± 0.78
|
2.36 ± 0.74
|
2.28 ± 0.82
|
|
FEV1 (% predicted)
|
82.7 ± 12.7
|
81.3 ± 13.3
|
83.9 ± 12.2
|
|
FEV1/FVC (%)
|
73.4 ± 12.8
|
73.7 ± 12.0
|
73.2 ± 13.2
|
|
DLco (% predicted)
|
78.1 ± 9.9
|
77.9 ± 9.5
|
78.4 ± 10.3
|
|
Laboratory parameters
| | | |
|
White blood cell (× 109/L)
|
6.59 (5.23–8.27)
|
6.34 (5.07–8.25)
|
6.79 (5.34–8.33)
|
|
Platelet count (× 109/L)
|
237 (194–293)
|
232 (192–288)
|
242 (196–300)
|
|
Prothrombin time (s)
|
11.2 (9.9–12.6)
|
11.1 (10.0–12.4)
|
11.3 (9.8–12.7)
|
|
Fibrinogen (mg/dL)
|
285.1 ± 104.1
|
283.6 ± 104.6
|
286.6 ± 103.7
|
|
C-reactive protein (mg/dL)
|
0.8 (0.5–1.2)
|
0.8 (0.5–1.1)
|
0.8 (0.5–1.2)
|
|
Procalcitonin (pg/ml)
|
0.10 (0.08–0.12)
|
0.10 (0.08–0.11)
|
0.10 (0.08–0.12)
|
