|
Primary endpoint
| | | | |
|
The number of patients with a single moment of SpO2 < 90% during bronchoscopy, no. (%)
|
163 (20.7)
|
49 (12.5)
|
114 (28.8)
|
< 0.001
|
|
Secondary endpoint
| | | | |
|
Duration of bronchoscopy (s)
|
780 (592–965)
|
685 (485–850)
|
800 (614–990)
|
< 0.001
|
|
Other endpoints
| | | | |
|
Duration of SpO2 < 90% (s)
|
98 (29–130)
|
22 (14–27)
|
115 (96–137)
|
< 0.001
|
|
The number of patients with procedural discontinuation no. (%)
|
141 (17.9)
|
39 (9.9)
|
102 (25.8)
|
< 0.001
|
|
Bronchoalveolar lavage
| | | | |
|
Volume of fluid instilled (ml)
|
60 (40–100)
|
60 (40–100)
|
60 (40–100)
|
0.751
|
|
Volume of fluid recovered (ml)
|
20 (15–45)
|
22 (15–45)
|
20 (15–45)
|
0.483
|
|
Bronchial brushing, no. (%)
|
736 (93.4)
|
367 (93.6)
|
369 (93.2)
|
0.803
|
|
Endobronchial biopsy, no. (%)
|
677 (85.9)
|
337 (86.0)
|
340 (85.9)
|
0.964
|
|
Transbronchial lung biopsy, no. (%)
|
235 (29.8)
|
115 (29.3)
|
120 (30.3)
|
0.767
|
|
Events during bronchoscopy, no. (%)
| | | | |
|
Agitation
|
119 (15.1)
|
43 (11.0)
|
76 (19.2)
|
0.001
|
|
Bronchospasm
|
30 (3.8)
|
12 (3.1)
|
18 (4.5)
|
0.276
|
|
Arrhythmias
| | | |
0.559
|
|
Ventricular arrhythmias
|
8 (1.0)
|
3 (0.8)
|
5 (1.3)
|
0.484
|
|
Supraventricular tachycardias
|
16 (2.0)
|
4 (1.0)
|
12 (3.0)
|
0.045
|
|
Premature atrial contractions
|
25 (3.2)
|
11 (2.8)
|
14 (3.5)
|
0.559
|
|
Premature ventricular contraction
|
14 (1.8)
|
5 (1.3)
|
9 (2.3)
|
0.289
|
|
Hypertension (systolic blood pressure > 180 mmHg)
|
124 (15.7)
|
64 (16.3)
|
60 (15.2)
|
0.651
|
|
Epistaxis
|
40 (5.1)
|
18 (4.6)
|
22 (5.6)
|
0.538
|
|
Mucosal bleeding
|
204 (25.9)
|
103 (26.3)
|
101 (25.5)
|
0.805
|
|
Complications of bronchoscopy, no. (%)
| | | | |
|
Fever
|
162 (20.6)
|
78 (19.9)
|
84 (21.2)
|
0.648
|
|
Pneumothorax
|
33 (4.2)
|
10 (2.6)
|
23 (5.8)
|
0.022
|
|
Hemorrhage
|
51 (6.5)
|
25 (6.4)
|
26 (6.6)
|
0.915
|
