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Table 3 Comparison of vital signs between the modified high-flow nasal cannula oxygen and the conventional oxygen therapy groups

From: Modified high-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients undergoing bronchoscopy: a randomized clinical trial

Characteristic Group Pre-5 min (n = 392/396) The lowest SpO2, the highest respiratory rate, heart rate, and mean arterial pressure (n = 392/396) Post-5 min (n = 392/396) Post-10 min (n = 392/396) Post-2 h (n = 392/396) Post-6 h (n = 392/396) Post-24 h (n = 392/396) pa
SpO2 (%) MHFNC 97.4 ± 1.6 94.1 ± 3.2 95.4 ± 2.3 94.7 ± 2.7 95.5 ± 1.8 95.7 ± 1.8 96.0 ± 1.7 < 0.001
  Control 97.3 ± 1.5 90.5 ± 3.8 92.1 ± 2.6 93.4 ± 2.9 95.3 ± 2.1 95.7 ± 1.9 95.9 ± 1.8 < 0.001
  pc 0.268 < 0.001 < 0.001 < 0.001 0.348 0.869 0.493 0.003b
Respiratory rate (bpm) MHFNC 17 ± 5 26 ± 7 19 ± 5 19 ± 4 18 ± 3 17 ± 3 17 ± 3 < 0.001
  Control 18 ± 4 28 ± 6 21 ± 5 20 ± 4 18 ± 3 17 ± 3 17 ± 3 < 0.001
  pc 0.196 < 0.001 < 0.001 0.005 0.693 0.694 0.973 0.001b
Heart rate (beats/min) MHFNC 84 ± 15 112 ± 18 94 ± 16 93 ± 16 83 ± 10 82 ± 10 81 ± 10 < 0.001
  Control 83 ± 15 116 ± 21 97 ± 18 94 ± 16 82 ± 10 81 ± 11 80 ± 10 < 0.001
  pc 0.305 0.015 0.037 0.377 0.167 0.818 0.334 0.465b
Mean arterial pressure (mmHg) MHFNC 95 ± 13 108 ± 15 102 ± 14 104 ± 17 95 ± 10 94 ± 10 94 ± 9 < 0.001
  Control 94 ± 12 110 ± 18 103 ± 16 104 ± 16 96 ± 10 95 ± 10 94 ± 10 < 0.001
  pc 0.454 0.256 0.233 0.890 0.541 0.342 0.580 0.402b
  1. FiO2 the fraction of inspired oxygen, SpO2 peripheral arterial oxygen saturation
  2. pa for overall comparisons of differences in each group over time
  3. pb for overall comparisons of differences between groups over time
  4. pc for comparisons of differences between groups at each time point