Fig. 1

A Enrichment map from the functional enrichment analysis using the Enrichr tool. Nodes represent gene ontology–biological process (GO-BP) gene sets, and GO-BPs of interest are labeled. Their color intensity and size are proportional to the enrichment score and the degree, respectively. The edge thickness represents the degree of overlap between gene sets, and only edges with a Jaccard similarity coefficient larger than 0.10 are visualized. B Functional enrichment analysis of DEGs for KEGG pathways. Point size and color express the odds ratios and adjusted p values. C GSEA plot of the p53 signaling pathway