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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis

Fig. 3

Pathway and cell subset-driven characterization. A Pathway enrichment scores of IPF subgroups. B Cell subset enrichment score of IPF subgroups. Cell scores predict relative enrichment for cell types. C Expression levels of cilia-associated genes and ciliated cell markers. D Forced vital capacity (FVC) and diffusing capacity of the lung for carbon monoxide (DLCO). Pulmonary function testing was performed within 6 months before lung tissue sampling, and the data on FVC and DLCO was available for 328 patients (C1 = 160, C2 = 168). Differences across the two subgroups were evaluated using an unpaired t-test. *P < 0.01; **P < 0.01; ***P < 0.001

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