Skip to main content

Table 1 Clinical characteristics of the LTX candidates (n = 269) based on the disease category

From: Waiting time and mortality rate on lung transplant candidates in Japan: a single-center retrospective cohort study

 

Total

Obstructive

Vascular

Suppurative

Fibrosis

Allogeneic

p value

n = 269

n = 61

n = 53

n = 21

n = 114

n = 20

Age, median (IQR)

44 (31–51)

45 (37–49)

28 (20–38)

47 (39–50)

48 (39–55)

33 (21–47)

< .001

Sex, male (%)

136 (50.6)

17 (27.9)

22 (41.5)

11 (52.4)

77 (53.5)

9 (45.0)

0.017

Body mass index (kg/m2), median (IQR)

19.47 (16.89–23.51)

18.66 (16.68–21.10)

19.57 (17.73–23.50)

18.82 (16.34–20.47)

21.25 (17.19–25.70)

15.90 (14.37–17.32)

< .001

Blood type, n (%)

     

0.1875

A

103 (38.3)

30 (49.2)

18 (33.9)

5 (23.8)

44 (38.6)

6 (30.0)

 

O

71 (26.4)

12 (19.7)

11 (20.8)

10 (47.6)

33 (28.9)

5 (25.0)

 

B

73 (27.1)

17 (27.9)

17 (32.1)

5 (23.8)

26 (22.8)

8 (40.0)

 

AB

22 (8.2)

2 (3.3)

7 (13.2)

1 (4.7)

11 (9.6)

1 (5.0)

 

Pre-transplant condition, n (%)

     

Malignancy

26 (9.7)

2 (3.3)

0 (0.0)

1 (4.8)

10 (8.8)

13 (65.0)

< .001

Connective tissue disorders

47 (17.5)

2 (3.3)

5 (9.4)

2 (9.5)

35 (30.7)

3 (15.0)

0.175

Supplemental oxygen

227 (84.4)

51 (83.6)

46 (86.8)

19 (90.5)

92 (80.7)

19 (95.0)

0.999

Pulmonary function, median (IQR)

    

Predicted FVC (%)

58.0 (40.9–80.8)

80.7 (58.3–87.7)

83.2 (71.0–94.9)

48.3 (37.6–61.7)

44.5 (30.4–59.7)

43.4 (29.9–50.6)

< .001

6-min walk (m)

300 (199–375)

260 (187–343)

386 (296–376)

261 (187–338)

288 (163–372)

249 (168–345)

< .001

Estimated RVP (mmHg)

38.0 (26.0–59.5)

32.0 (26.0–42.0)

89.5 (73.0–118.0)

38.0 (20.0–61.0)

34.0 (25.0–47.0)

27.5 (22.0–39.5)

< .001

Laboratory, median (IQR)

     

Hemoglobin (g/dL)

13.6 (12.1–14.9)

13.7 (13.0–14.8)

13.3 (11.8–15.3)

12.1 (11.6–14.6)

13.7 (12.4–15.1)

12.3 (11.1–14.6)

0.127

Albumin (g/dL)

3.9 (3.6–4.2)

4.1 (3.9–4.3)

4.2 (3.8–4.4)

3.5 (3.2–3.8)

3.8 (3.5–4.1)

3.9 (3.6–4.0)

< .001

Creatinine (mg/dL)

0.68 (0.57–0.79)

0.62 (0.53–0.71)

0.70 (0.60–0.80)

0.60 (0.48–0.70)

0.70 (0.59–0.83)

0.55 (0.47–0.80)

0.005

Outcomes, n (%)

     

< .001

Transplanted

100 (37.2)

33 (54.1)

19 (35.8)

11 (52.4)

31 (27.2)

6 (30.0)

 

Dead

97 (36.1)

8 (13.1)

17 (32.1)

7 (33.3)

58 (50.9)

7 (35.0)

 

Waiting (on March 2021)

72 (26.8)

20 (32.8)

17 (32.1)

3 (14.3)

25 (21.9)

7 (35.0)

 

Wait time, median day (IQR)

     

Time to transplant (n = 100)

796 (579–1056)

981 (678–1132)

959 (602–2015)

758 (676–943)

730 (331–849)

730 (331–849)

0.059

Time to death (n = 97)

323 (129–528)

599 (176–891)

465 (201–897)

196 (5–410)

315 (113–513)

287 (132–449)

0.083

Time to events/censoring (n = 269)

573 (283–991)

930 (538–1193)

959 (483–1804)

685 (203–954)

445 (16–641)

403 (240–640)

< .001

  1. FVC forced vital capacity, IQR interquartile range, RVP right ventricular pressure