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Table 1 Baseline characteristics of the patients according to diagnosis of ARDS

From: Predicting acute respiratory distress syndrome in influenza pneumonia patients using delta mean platelet volume

Variables Total (n = 212) Diagnosis p value
ARDS (n = 56) Non-ARDS (n = 156)
Demographic data     
Sex (female) 110 (51.9) 28 (50) 82 (52.6) 0.742
Age (years) 71 (59–79) 74 (64.25–83) 70 (58–78.75) 0.069
Underlying diseases     
Diabetes mellitus 57 (26.9) 16 (28.6) 41 (26.3) 0.740
Hypertension 79 (37.3) 25 (44.6) 54 (34.6) 0.183
History of malignancy 25 (11.8) 4 (7.1) 21 (13.5) 0.209
Immunosuppression 15 (7.1) 0 15 (9.6) 0.016
Chronic kidney disease 28 (13.2) 10 (17.9) 18 (11.5) 0.231
Coronary artery disease 20 (9.4) 6 (10.7) 14 (9) 0.702
Stroke 21 (9.9) 7 (12.5) 14 (9) 0.449
Cirrhosis 11 (5.2) 2 (3.6) 9 (5.8) 0.525
Chronic airway disease 35 (16.5) 7 (12.5) 28 (17.9) 0.346
Congestive heart failure     
Clinical data     
Charlson comorbidity index 2 (1–4) 2 (1–4) 2 (1–4.75) 0.297
SOFA 2 (1–3) 3 (2–4) 2 (1–3) < 0.001
APACHE II 12 (8–15) 14 (12.0–18.75) 12 (7–13) < 0.001
NEWS 6 (4–8) 7 (6–9) 5 (3–7) < 0.001
CURB-65 2 (1–2) 2 (2–3) 2 (1–2) < 0.001
PSI 92 (74–107) 99.5 (87.25–108.75) 88 (69–103.75) 0.006
Influenza type     
A 171 (80.7) 43 (76.8) 128 (82.1) 0.392
B 22 (19.8) 13 (23.2) 28 (17.9) 0.256
Test positive     
Rapid (IFA) 120 (56.6) 25 (44.6) 61 (39.1) 0.031
PCR 92 (43.4) 31 (55.4) 95 (60.9) 0.035
Haemoculture positive results 5/189 1/55 4/134 0.650
Sputum culture positive results 55/153 22/53 33/100 0.297
Interval between collection of CBC day 1 and day 2 (hours) 13 (7–17) 12 (7–16) 13 (7–18) 0.338
Laboratory results     
Hb level day 1 (g/dL) 11.9 (10.0–13.47) 12.35 (9.68–13.42) 11.75 (10.12–13.47) 0.478
WBC count day 1 (× 103/µL) 9.66 (6.6–13.1) 10.74 (6.97–13.83) 9.2 (6.34–12.74) 0.024
PMN (%) 78 (69–85) 79.1 (69–84.6) 77.7 (68.4–85.15) 0.871
Lymphocytes (%) 10.85 (6.17–17.85) 8.9 (5.9–14.4) 12 (7–19.1) 0.008
Platelet count day 1 (× 103/µL) 214 (161.2–280) 220.96 (152.25–289) 229.12 (162.25–280) 0.429
MPV day 1 (fL) 10 (9.4–10.6) 10.04 (9.45–10.4) 10.05 (9.4–10.6) 0.874
MPR day 1 4.64 (3.4–6.3) 5.12 (3.27–6.64) 4.5 (3.37–6.29) 0.512
MPV day 2 (fL) 10.5 (9.9–11.1) 11 (10.3–11.5) 10.3 (9.6–10.9) < 0.001
MPR day 2 5.22 (3.8–7.2) 6.41 (4.45–8.36) 4.85 (3.63–6.99) 0.002
Delta MPV (fL) 0.4 (0.1–0.9) 1.0 (0.7–1.2) 0.2 (0–0.5) < 0.001
Outcomes     
Invasive mechanical ventilation 99 (46.7) 54 (96.4) 45 (28.8) < 0.001
Length of hospital stay (days) 9 (5–19) 21 (12–32.75) 7 (4–11) < 0.001
In-hospital mortality 19 (9) 15 (26.8) 4 (2.6) < 0.001
  1. Data are presented as median (interquartile range) or n (%)
  2. APACHE II, acute physiology and chronic health evaluation II; ARDS, acute respiratory distress syndrome; CURB-65, confusion, urea nitrogen, respiratory rate, blood pressure, 65 years of age and older; IFA, indirect fluorescent antibody; MPR, mean platelet count volume to platelet count ratio; MPV, mean platelet volume; NEWS, national early warning score; PCR, polymerase chain reaction; PMN, polymorphonuclear leukocytes; PSI, pneumonia severity index; SOFA, sequential organ failure assessment; WBC, white blood cells