| | |
COPD
|
OHS
|
NMD
|
Non-CF BC or TB
|
SCOLIOSIS
|
ALS
|
Other Diagnoses
|
|---|
|
n
| |
388
|
264
|
180
|
92
|
65
|
58
|
58
|
|
AGE (years)
|
mean (SD)
|
65.6 (10)
|
56.8 (14.4)
|
31.5 (15.1)
|
52.4 (19.1)
|
53.3 (19)
|
55.5 (12.1)
|
53.7 (20.5)
|
|
FEMALE
|
n (%)
|
195 (50.3)
|
157 (59.5)
|
73 (40.6)
|
56 (60.9)
|
40 (61.5)
|
19 (32.8)
|
32(55.2)
|
|
BMI
|
mean (SD)
|
33.9 (10.1)
|
47.3 (9.6)
|
22.5 (6.8)
|
30.3 (8.8)
|
27.1 (8.4)
|
23 (4.4)
|
29.6(7.9)
|
|
Patients progression
|
|
ACTIVE
|
n (%)
|
203 (52.3)
|
196 (74.2)
|
136 (75.6)
|
43 (46.7)
|
49 (75.4)
|
22 (37.9)
|
26 (44.8)
|
|
DEAD
| |
144 (37.1)
|
39 (14.8)
|
37 (20.6)
|
38 (41.3)
|
13 (20)
|
31 (53.5)
|
27 (46.6)
|
|
DISCHARGED
| |
41 (10.6)
|
29 (11)
|
7 (3.9)
|
11 (12)
|
3 (4.6)
|
5 (8.6)
|
5 (8.6)
|
|
Lung function
|
|
FVC (%)
|
mean (SD)
|
59.2 (19.4)
|
69.1 (20.7)
|
36.7 (25.2)
|
49.7 (14.5)
|
36.1 (15.0)
|
45.5 (12.1)
|
46.2 (19.6)
|
|
FEV1 (%)
| |
37.2 (18.5)
|
67.7 (21.3)
|
38.2 (25.3)
|
32.9 (12.4)
|
34.0 (13.0)
|
48.0 (14.3)
|
37.5 (20.4)
|
|
FEV1/FVC (%)
| |
49,7 (16.3)
|
79 (10.1)
|
89.4 (13)
|
55.2 (14.2)
|
81.3(12.2)
|
83 (10.3)
|
67.1 (20.5)
|
|
Arterial blood gas
|
|
paO2 (mmHg)
|
mean (SD)
|
59.9 (14.1)
|
64 (15)
|
78.1 (21.2)
|
61 (14.4)
|
66.3 (17.7)
|
80.2 (17.8)
|
73.7 (25.8)
|
|
paCO2 (mmHg)
| |
61 (10)
|
59.2 (10.9)
|
53.9 (14.6)
|
61.5 (10.4)
|
61.9 (12.8)
|
53.5 (16.7)
|
57.1 (11.4)
|
|
HCO3− (mmol/L)
| |
32.7 (5.6)
|
31.6 (6.5)
|
29.2 (6.2)
|
33.5 (5)
|
34.1 (9.9)
|
28.5 (4.8)
|
32.9 (4.3)
|
|
Type of ventilation
|
|
NIV
|
n (%)
|
388 (100)
|
264 (100)
|
142 (78.9)
|
92 (100)
|
64 (98.5)
|
41 (70.7)
|
55 (94.8)
|
|
TIV
| |
0
|
0
|
38 (21.1)
|
0
|
1 (1.54)
|
17(29.3)
|
3 (5.17)
|
|
Time in HMV (months)
|
mean (SD)
|
32 (29.7)
|
42.3 (32.4)
|
32.5 (26.4)
|
34.7 (30.9)
|
46.1(33.3)
|
14.8 (10.4)
|
22.9 (22)
|
|
Compliance (h/day)
|
|
0–8
|
(%)
|
70.8
|
85.5
|
44.6
|
61
|
73.3
|
18.42
|
67.9
|
|
> 8 hasta 16
| |
27.9
|
14.5
|
38.8
|
39
|
24.4
|
36.84
|
25
|
|
> 16
| |
1.3
|
0
|
16.5
|
0
|
2.2
|
44.74
|
7.14
|
|
Ventilator settings
|
|
IPAP
|
mean (SD)
|
16.6 (3.3)
|
17.7 (3)
|
16.5 (4.7)
|
17.2 (3.6)
|
15.1 (3.3)
|
15.5 (4.2)
|
17.1 (3.9)
|
|
EPAP
| |
7.5 (1.3)
|
7.9 (1.4)
|
6.5 (1.3)
|
7.6 (1.4)
|
6.6(1,4)
|
6.6 (1.3)
|
7.4 (1.3)
|
|
Backup frequency rate
| |
15.5 (2.5)
|
15.2 (2.1)
|
15 (3.1)
|
14.7 (2.3)
|
15.3(2.5)
|
16.4 (3.9)
|
15.4 (2.9)
|
- COPD chronic obstructive pulmonary disease, OHS obesity hypoventilation syndrome, NMD neuromuscular disease, non-CF BC or TB non-cystic fibrosis bronchiectasis or tuberculosis, ALS amyotrophic lateral sclerosis, OTHER DIAGNOSES cystic fibrosis, pulmonary fibrosis, phrenic paralysis, posttransplant bronchiolitis, BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, NIV non-invasive ventilation, TIV tracheostomy invasive ventilation, HMV home mechanical ventilation, IPAP inspiratory positive airway pressure, EPAP expiratory positive airway pressure
