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Table 3 Baseline variables of active, dead, and discharged patients as of August 1, 2018, (n = 1105)

From: Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017

   COPD OHS NMD Non-CF BC or TB SCOLIOSIS ALS Other Diagnoses
n   388 264 180 92 65 58 58
AGE (years) mean (SD) 65.6 (10) 56.8 (14.4) 31.5 (15.1) 52.4 (19.1) 53.3 (19) 55.5 (12.1) 53.7 (20.5)
FEMALE n (%) 195 (50.3) 157 (59.5) 73 (40.6) 56 (60.9) 40 (61.5) 19 (32.8) 32(55.2)
BMI mean (SD) 33.9 (10.1) 47.3 (9.6) 22.5 (6.8) 30.3 (8.8) 27.1 (8.4) 23 (4.4) 29.6(7.9)
Patients progression
ACTIVE n (%) 203 (52.3) 196 (74.2) 136 (75.6) 43 (46.7) 49 (75.4) 22 (37.9) 26 (44.8)
DEAD   144 (37.1) 39 (14.8) 37 (20.6) 38 (41.3) 13 (20) 31 (53.5) 27 (46.6)
DISCHARGED   41 (10.6) 29 (11) 7 (3.9) 11 (12) 3 (4.6) 5 (8.6) 5 (8.6)
Lung function
FVC (%) mean (SD) 59.2 (19.4) 69.1 (20.7) 36.7 (25.2) 49.7 (14.5) 36.1 (15.0) 45.5 (12.1) 46.2 (19.6)
FEV1 (%)   37.2 (18.5) 67.7 (21.3) 38.2 (25.3) 32.9 (12.4) 34.0 (13.0) 48.0 (14.3) 37.5 (20.4)
FEV1/FVC (%)   49,7 (16.3) 79 (10.1) 89.4 (13) 55.2 (14.2) 81.3(12.2) 83 (10.3) 67.1 (20.5)
Arterial blood gas
paO2 (mmHg) mean (SD) 59.9 (14.1) 64 (15) 78.1 (21.2) 61 (14.4) 66.3 (17.7) 80.2 (17.8) 73.7 (25.8)
paCO2 (mmHg)   61 (10) 59.2 (10.9) 53.9 (14.6) 61.5 (10.4) 61.9 (12.8) 53.5 (16.7) 57.1 (11.4)
HCO3 (mmol/L)   32.7 (5.6) 31.6 (6.5) 29.2 (6.2) 33.5 (5) 34.1 (9.9) 28.5 (4.8) 32.9 (4.3)
Type of ventilation
NIV n (%) 388 (100) 264 (100) 142 (78.9) 92 (100) 64 (98.5) 41 (70.7) 55 (94.8)
TIV   0 0 38 (21.1) 0 1 (1.54) 17(29.3) 3 (5.17)
Time in HMV (months) mean (SD) 32 (29.7) 42.3 (32.4) 32.5 (26.4) 34.7 (30.9) 46.1(33.3) 14.8 (10.4) 22.9 (22)
Compliance (h/day)
0–8 (%) 70.8 85.5 44.6 61 73.3 18.42 67.9
 > 8 hasta 16   27.9 14.5 38.8 39 24.4 36.84 25
 > 16   1.3 0 16.5 0 2.2 44.74 7.14
Ventilator settings
IPAP mean (SD) 16.6 (3.3) 17.7 (3) 16.5 (4.7) 17.2 (3.6) 15.1 (3.3) 15.5 (4.2) 17.1 (3.9)
EPAP   7.5 (1.3) 7.9 (1.4) 6.5 (1.3) 7.6 (1.4) 6.6(1,4) 6.6 (1.3) 7.4 (1.3)
Backup frequency rate   15.5 (2.5) 15.2 (2.1) 15 (3.1) 14.7 (2.3) 15.3(2.5) 16.4 (3.9) 15.4 (2.9)
  1. COPD chronic obstructive pulmonary disease, OHS obesity hypoventilation syndrome, NMD neuromuscular disease, non-CF BC or TB non-cystic fibrosis bronchiectasis or tuberculosis, ALS amyotrophic lateral sclerosis, OTHER DIAGNOSES cystic fibrosis, pulmonary fibrosis, phrenic paralysis, posttransplant bronchiolitis, BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, NIV non-invasive ventilation, TIV tracheostomy invasive ventilation, HMV home mechanical ventilation, IPAP inspiratory positive airway pressure, EPAP expiratory positive airway pressure