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Table 4 Baseline variables and progression of COPD patients according to BMI (n = 176)

From: Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017

   COPD
BMI < 30 kg/m2
COPD
BMI ≥ 30 kg/m2
p value
n   62 114  
Gender
Male n (%) 33 (53.2) 60 (52.6)  
Female   29 (46.8) 54 (47.4)  
Age (years) mean (SD) 66.5 (10.1) 63.3 (8.9) 0.0169
Patient progression
Active patients n (%) 34 (54.8) 94 (82.5) 0.0001
Dead   28 (45.2) 20 (17.5) 0.0001
Lung function
FVC (%) mean (SD) 56.2 (17.4) 60.8 (18.2) 0.0678
FEV1 (%)   26.5 (10.6) 41.8 (19.3) 0.0001
FEV1/FVC (%)   38.4 (11.6) 54 (15.3) 0.0001
Arterial blood gas
paO2 (mmHg) mean (SD) 58.6 (13.2) 59.3 (10.8) 0.3886
paCO2 (mmHg)   62.2 (10.7) 59.8 (8.4) 0.0700
HCO3- (mmol/L)   31.3 (6.3) 32.3 (5.4) 0.1976
Time in HMV (months) mean (SD) 41 (31.9) 43.8 (31.8) 0.2921
Compliance (h/day)
0–8 (%) 66.7 69.6  
 > 8 to 16   30.9 30.4 0.432
 > 16   2.4 0  
Ventilator settings
IPAP mean (SD) 16 (3.1) 17.1 (3.7) 0.0650
EPAP   7.1 (1.2) 7.7 (1.4) 0.0204
Backup respiratory rate   15.3 (2.4) 15.7 (2.6) 0.1941
  1. COPD chronic obstructive pulmonary disease, BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, HMV home mechanical ventilation, IPAP inspiratory positive airway pressure, EPAP expiratory positive airway pressure