Table 4 Baseline variables and progression of COPD patients according to BMI (n = 176)
COPD BMI < 30 kg/m2 | COPD BMI ≥ 30 kg/m2 | p value | ||
|---|---|---|---|---|
n | 62 | 114 | ||
Gender | ||||
Male | n (%) | 33 (53.2) | 60 (52.6) | |
Female | 29 (46.8) | 54 (47.4) | ||
Age (years) | mean (SD) | 66.5 (10.1) | 63.3 (8.9) | 0.0169 |
Patient progression | ||||
Active patients | n (%) | 34 (54.8) | 94 (82.5) | 0.0001 |
Dead | 28 (45.2) | 20 (17.5) | 0.0001 | |
Lung function | ||||
FVC (%) | mean (SD) | 56.2 (17.4) | 60.8 (18.2) | 0.0678 |
FEV1 (%) | 26.5 (10.6) | 41.8 (19.3) | 0.0001 | |
FEV1/FVC (%) | 38.4 (11.6) | 54 (15.3) | 0.0001 | |
Arterial blood gas | ||||
paO2 (mmHg) | mean (SD) | 58.6 (13.2) | 59.3 (10.8) | 0.3886 |
paCO2 (mmHg) | 62.2 (10.7) | 59.8 (8.4) | 0.0700 | |
HCO3- (mmol/L) | 31.3 (6.3) | 32.3 (5.4) | 0.1976 | |
Time in HMV (months) | mean (SD) | 41 (31.9) | 43.8 (31.8) | 0.2921 |
Compliance (h/day) | ||||
0–8 | (%) | 66.7 | 69.6 | |
> 8 to 16 | 30.9 | 30.4 | 0.432 | |
> 16 | 2.4 | 0 | ||
Ventilator settings | ||||
IPAP | mean (SD) | 16 (3.1) | 17.1 (3.7) | 0.0650 |
EPAP | 7.1 (1.2) | 7.7 (1.4) | 0.0204 | |
Backup respiratory rate | 15.3 (2.4) | 15.7 (2.6) | 0.1941 | |