Fig. 4

Establishment and assessment of the risk prognosis signatures through LASSO and multivariate Cox regression analysis; Correlation between risk prognosis signatures with clinical and immune characteristics. A LASSO coefficient profiles of 16 prognostic immune-related genes. B 10-times cross-validation for tuning parameter selection in the LASSO model. C Heatmap of the expression of 11 risk genes after multivariate Cox regression analysis. D Kaplan–Meier curves of overall survival (OS) for the NSCLC patients in high- and low-risk groups. E Time-dependent receiver operating curves of 1/3/5-years survival for NSCLC patients using risk scores. F The distribution of risk scores and the relationship between risk scores and survival times. G The different levels of risk scores between different phenotypic terms. H The discriminative levels of immune cells infiltration between high- and low-risk groups. I The distinguishing expression levels of immune check points between high- and low-risk groups in NSCLC patients. *p < 0.05; **p < 0.01; ***p < 0.001