Skip to main content

Table 2 Drug-resistant profiles among newly diagnosed pulmonary TB patients with different BMI

From: Association between body mass index and newly diagnosed drug-resistant pulmonary tuberculosis in Shandong, China from 2004 to 2019

Drug resistance

Normal weight DR-TB cases (1210/6417, 18.86%)

Underweight DR-TB cases (387/2121, 18.25%)

Overweight DR-TB cases (76/373, 20.38%)

Obese DR-TB cases (11/46, 23.91%)

P value

Underweight group vs Normal weight group

Overweight group vs Normal weight group

Obese group vs Normal weight group

DR-TB

1210 (18.86%)

387 (18.25%)

76 (20.38%)

11 (23.91%)

0.532

0.467

0.383

Any resistance to first-line drug

       

INH

663 (10.33%)

218 (10.28%)

47 (12.6%)

5 (10.87%)

0.944

0.164

0.905

RFP

311 (4.85%)

94 (4.43%)

23 (6.17%)

0 (0.00%)

0.436

0.252

0.171

EMB

95 (1.48%)

31 (1.46%)

6 (1.61%)

0 (0.00%)

0.950

0.842

1.000

SM

863 (13.45%)

246 (11.6%)

60 (16.09%)

9 (19.57%)

0.028*

0.149

0.226

MR-TB (Total)

718 (11.19%)

249 (11.74%)

36 (9.65%)

8 (17.39%)

0.488

0.358

0.184

INH

209 (3.26%)

92 (4.34%)

9 (2.41%)

2 (4.35%)

0.019*

0.369

0.662

RFP

58 (0.9%)

18 (0.85%)

1 (0.27%)

0 (0.00%)

0.815

0.379

1.000

EMB

12 (0.19%)

5 (0.24%)

1 (0.27%)

0 (0.00%)

0.662

0.521

1.000

SM

436 (6.79%)

130 (6.13%)

25 (6.7%)

6 (13.04%)

0.286

0.945

0.094

Others

3 (0.05%)

4 (0.19%)

0 (0.00%)

0 (0.00%)

0.069

1.000

1.000

MDR-TB (Total)

219 (3.41%)

65 (3.06%)

20 (5.36%)

0 (0.00%)

0.438

0.047*

0.407

MDR1: INH + RFP

48 (0.75%)

15 (0.71%)

4 (1.07%)

0 (0.00%)

0.849

0.531

1.000

MDR2: INH + RFP + EMB + SM

48 (0.75%)

16 (0.75%)

4 (1.07%)

0 (0.00%)

0.977

0.531

1.000

MDR3: INH + RFP + SM

108 (1.68%)

30 (1.41%)

12 (3.22%)

0 (0.00%)

0.395

0.029*

1.000

Others

15 (0.23%)

4 (0.19%)

0 (0.00%)

0 (0.00%)

1.000

1.000

1.000

PDR-TB

270 (4.21%)

72 (3.39%)

20 (5.36%)

3 (6.52%)

0.098

0.284

0.444

PDR1: INH + EMB

6 (0.09%)

2 (0.09%)

1 (0.27%)

0 (0%)

1.000

0.327

1.000

PDR2: INH + SM

219 (3.41%)

55 (2.59%)

17 (4.56%)

3 (6.52%)

0.063

0.241

0.209

PDR3: RFP + SM

27 (0.42%)

8 (0.38%)

2 (0.54%)

0 (0.00%)

0.785

0.672

1.000

PDR4: INH + EMB + SM

10 (0.16%)

3 (0.14%)

0 (0.00%)

0 (0.00%)

1.000

1.000

1.000

Others

8 (0.12%)

4 (0.19%)

0 (0.00%)

0 (0.00%)

0.507

1.000

1.000

  1. TB, tuberculosis; DR-TB, drug-resistant tuberculosis; MR-TB, mono-resistant tuberculosis; MDR-TB, multidrug resistant tuberculosis; PDR-TB, polydrug resistant tuberculosis; EMB, ethambutol; INH, isoniazid; RFP, rifampin; SM, streptomycin; BMI, body mass index;*P < 0.05
  2. Underweight: BMI < 18.5 kg/m2; Normal weight: 18.5 kg/m2 ≥ BMI ≤ 24.9 kg/m2; Overweight: 25 kg/m2 ≥ BMI ≤ 29.9 kg/m2; Obese: BMI ≥ 30 kg/m2