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Table 2 Drug-resistant profiles among newly diagnosed pulmonary TB patients with different BMI

From: Association between body mass index and newly diagnosed drug-resistant pulmonary tuberculosis in Shandong, China from 2004 to 2019

Drug resistance Normal weight DR-TB cases (1210/6417, 18.86%) Underweight DR-TB cases (387/2121, 18.25%) Overweight DR-TB cases (76/373, 20.38%) Obese DR-TB cases (11/46, 23.91%) P value
Underweight group vs Normal weight group Overweight group vs Normal weight group Obese group vs Normal weight group
DR-TB 1210 (18.86%) 387 (18.25%) 76 (20.38%) 11 (23.91%) 0.532 0.467 0.383
Any resistance to first-line drug        
INH 663 (10.33%) 218 (10.28%) 47 (12.6%) 5 (10.87%) 0.944 0.164 0.905
RFP 311 (4.85%) 94 (4.43%) 23 (6.17%) 0 (0.00%) 0.436 0.252 0.171
EMB 95 (1.48%) 31 (1.46%) 6 (1.61%) 0 (0.00%) 0.950 0.842 1.000
SM 863 (13.45%) 246 (11.6%) 60 (16.09%) 9 (19.57%) 0.028* 0.149 0.226
MR-TB (Total) 718 (11.19%) 249 (11.74%) 36 (9.65%) 8 (17.39%) 0.488 0.358 0.184
INH 209 (3.26%) 92 (4.34%) 9 (2.41%) 2 (4.35%) 0.019* 0.369 0.662
RFP 58 (0.9%) 18 (0.85%) 1 (0.27%) 0 (0.00%) 0.815 0.379 1.000
EMB 12 (0.19%) 5 (0.24%) 1 (0.27%) 0 (0.00%) 0.662 0.521 1.000
SM 436 (6.79%) 130 (6.13%) 25 (6.7%) 6 (13.04%) 0.286 0.945 0.094
Others 3 (0.05%) 4 (0.19%) 0 (0.00%) 0 (0.00%) 0.069 1.000 1.000
MDR-TB (Total) 219 (3.41%) 65 (3.06%) 20 (5.36%) 0 (0.00%) 0.438 0.047* 0.407
MDR1: INH + RFP 48 (0.75%) 15 (0.71%) 4 (1.07%) 0 (0.00%) 0.849 0.531 1.000
MDR2: INH + RFP + EMB + SM 48 (0.75%) 16 (0.75%) 4 (1.07%) 0 (0.00%) 0.977 0.531 1.000
MDR3: INH + RFP + SM 108 (1.68%) 30 (1.41%) 12 (3.22%) 0 (0.00%) 0.395 0.029* 1.000
Others 15 (0.23%) 4 (0.19%) 0 (0.00%) 0 (0.00%) 1.000 1.000 1.000
PDR-TB 270 (4.21%) 72 (3.39%) 20 (5.36%) 3 (6.52%) 0.098 0.284 0.444
PDR1: INH + EMB 6 (0.09%) 2 (0.09%) 1 (0.27%) 0 (0%) 1.000 0.327 1.000
PDR2: INH + SM 219 (3.41%) 55 (2.59%) 17 (4.56%) 3 (6.52%) 0.063 0.241 0.209
PDR3: RFP + SM 27 (0.42%) 8 (0.38%) 2 (0.54%) 0 (0.00%) 0.785 0.672 1.000
PDR4: INH + EMB + SM 10 (0.16%) 3 (0.14%) 0 (0.00%) 0 (0.00%) 1.000 1.000 1.000
Others 8 (0.12%) 4 (0.19%) 0 (0.00%) 0 (0.00%) 0.507 1.000 1.000
  1. TB, tuberculosis; DR-TB, drug-resistant tuberculosis; MR-TB, mono-resistant tuberculosis; MDR-TB, multidrug resistant tuberculosis; PDR-TB, polydrug resistant tuberculosis; EMB, ethambutol; INH, isoniazid; RFP, rifampin; SM, streptomycin; BMI, body mass index;*P < 0.05
  2. Underweight: BMI < 18.5 kg/m2; Normal weight: 18.5 kg/m2 ≥ BMI ≤ 24.9 kg/m2; Overweight: 25 kg/m2 ≥ BMI ≤ 29.9 kg/m2; Obese: BMI ≥ 30 kg/m2