Influence of nocturnal hypoxemia on follow-up course after type B acute aortic syndrome

BMC Pulmonary Medicine

Table 4 Associations of nocturnal hypoxemia parameters with aortic diameters according to acute treatment strategy adjusted for age, BMI, sex, diabetes and systolic blood pressure

Aortic diameters	Ventilatory parameters	Population with medical therapy alone, n = 71			Population with aortic stent requirement in acute phase, n = 32			p*
Aortic diameters	Ventilatory parameters	β (SD)	R^2†	p value	β (SD)	R^2†	p value	p*
False lumen TD aorta	ODI^a	− 0.281 (1.496)	0.181	0.85	4.113 (2.607)	0.191	0.13	0.12
	AHI^b	0.556 (1.089)	0.176	0.61	4.954 (2.142)	0.26	0.029	0.061
	Lowest nocturnal oxygen saturation	− 0.236 (0.185)	0.192	0.21	− 0.266 (0.425)	0.119	0.54	0.48
	Mean nocturnal oxygen saturation	− 0.225 (0.550)	0.177	0.68	− 0.547 (1.174)	0.111	0.65	0.81
	Percentage of nocturnal time under a saturation of 90%^a	0.299 (0.982)	0.176	0.76	1.654 (1.620)	0.14	0.32	0.66
TD diameter of the aorta	ODI^a	− 0.721 (1.315)	0.136	0.59	3.653 (2.082)	0.323	0.093	0.018
	AHI^b	0.897 (0.942)	0.149	0.34	3.321 (1.851)	0.3	0.085	0.067
	Lowest nocturnal oxygen saturation	0.130 (0.161)	0.156	0.42	− 0.511 (0.327)	0.321	0.13	0.06
	Mean nocturnal oxygen saturation	− 0.227 (0.476)	0.148	0.63	− 1.543 (0.919)	0.296	0.11	0.15
	Percentage of nocturnal time under a saturation of 90%^a	− 0.227 (0.848)	0.147	0.79	3.111 (1.205)	0.384	0.016	0.016
Ascending aorta diameter	ODI^a	1.026 (0.786)	0.145	0.2	0.411 (0.837)	0.673	0.63	0.6
	AHI^b	0.852 (0.570)	0.201	0.14	− 0.300 (0.729)	0.684	0.68	0.89
	Lowest nocturnal oxygen saturation	0.100 (0.092)	0.154	0.28	− 0.150 (0.127)	0.695	0.25	0.048
	Mean nocturnal oxygen saturation	− 0.176 (0.286)	0.164	0.54	0.044 (0.362)	0.675	0.9	0.49
	Percentage of nocturnal time under a saturation of 90%^a	0.568 (0.503)	0.176	0.26	0.609 (0.492)	0.694	0.23	0.21

The results were highlighted (bold) when the p value was inferior or equal to 0.05
Abbreviations. TD: Thoracic descending, ODI: Oxygen desaturation index, AHI: Apnea–hypopnea index
^aAfter logarithm + 1 transformation
^bAfter logarithm transformation
*For heterogeneity
^†Partial R squared values calculated in multiple linear regression models

ISSN: 1471-2466