Table 2 Respiratory function indices in patients with CTEPH
| Â | Measured values | Expected values | p value |
|---|---|---|---|
VC (L) | 2.55 (2.05–3.07) | 2.57 (2.33–2.92) | < 0.001** |
%VC | 94.8 (83.1–101.7) |  |  |
FVC (L) | 2.55 (1.98–3.00) | 2.48 (2.26–2.83) | < 0.001** |
%FVC | 94.6 (84.2–105.1) |  |  |
FEV1.0 (L) | 1.91 (1.47–2.32) | 2.04 (1.82–2,46) | < 0.001** |
FEV1.0/FVC (%) | 76.0 (70.0–82.1) | 81.9 (79.3–85.9) | < 0.001** |
%FEV1.0 | 83.6 (73.8–98.3) |  |  |
MMF (L) | 1.40 (0.87–2.17) | 2.60 (2.30–3.10) | < 0.001** |
%MMF | 48.9 (35.1–71.6) |  |  |
\({\dot{\text{V}}}\)50 | 2.02 (1.28–2.75) | 2.95 (2.66–3.5) | < 0.001** |
%\({\dot{\text{V}}}\)50 | 59.9 (42.9–82.6) |  |  |
\({\dot{\text{V}}}\)25 (L) | 0.47 (0.29–0.82) | 1.06 (0.87–1.39) | < 0.001** |
%\({\dot{\text{V}}}\)25 | 41.8 (29.0–58.5) |  |  |
PEF (L/s) | 5.54 (4.42–6.67) | 5.62 (5.37–6.08) | < 0.001** |
> 5% of ATI, n (%) | 24 (17.8%) |  |  |
Restrictive ventilatory impairment, n (%) | 22 (16.3%) | Â | Â |
Obstructive ventilatory impairment, n (%) | 34 (25.2%) | Â | Â |
Mixed ventilatory impairment, n (%) | 3 (2.2%) | Â | Â |
DLco (mL/min/mmHg) | 13.1 (10.9–16.0) | 17.0 (15.1–20.1) | < 0.001** |
%DLco | 77.0 (64.8–86.5) |  |  |
TLC (L) | 4.77 (3.92–5.64) | 4.44 (4.11–4.97) | N.S |
RV (L) | 1.86 (1.58–2.24) | 1.82 (1.69–1.96) | N.S |
RV/TLC (%) | 39.9 (35.4–43.9) |  |  |