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Table 4 Baseline characteristics and respiratory function indices subdivided into groups according to median %FEV1.0

From: Vascular involvement in chronic thromboembolic pulmonary hypertension is associated with spirometry obstructive impairment

 

%FEV1.0 < 83.6%

%FEV1.0 ≧ 83.6%

p value

Age (years)

58.7 ± 1.7

62.2 ± 1.4

N.S

Male/female, n

19/48

8/60

0.0148*

Body weight (kg)

57.2 ± 1.5

52.8 ± 1.05

0.0339*

BMI (kg/m2)

22.4 ± 0.5

21.8 ± 0.3

N.S

WHO-FC (I: II: III: IV)

6/34/26/1

4/40/24/0

N.S

Type (Occult/Recurrent)

40/27

40/28

N.S

Hb (g/dL)

13.9 ± 0.2

13.6 ± 0.2

N.S

BNP (pg/mL)

296 ± 51

162 ± 27

0.0098**

CRP (g/dL)

0.27 ± 0.06

0.21 ± 0.05

0.0173*

ATIII (%)

97.4 ± 1.8

100.3 ± 1.6

N.S

Systolic SBP

123 ± 3

129 ± 2

0.0346*

Diastolic SBP

73 ± 2

74 ± 2

N.S

mPAP (mmHg)

45.1 ± 1.3

41.1 ± 1.2

0.0331*

PVR (dyne sec cm−5)

815 ± 45

689 ± 34

0.0334*

RAP (mmHg)

10.1 ± 0.53

7.65 ± 0.43

0.0008**

CO (L/min)

4.05 ± 0.14

4.23 ± 0.13

N.S

CI (L/min/m2)

2.51 ± 0.08

2.77 ± 0.09

0.0307*

CTA obstruction score

30.1 ± 1.3

21.6 ± 1.2

< 0.0001**

  1. Values are expressed as the mean ± standard error of the mean
  2. BMI, body mass index; WHO-FC, WHO-functional class; Hb, hemoglobin; BNP, brain natriuretic peptide; CRP, C-reactive protein; AT III, antithrombin III, SBP, systemic blood pressure; PAP, pulmonary arterial pressure; PVR, pulmonary vascular resistance; CO, cardiac output; CI, cardiac index
  3. *p < 0.05; **p < 0.01
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BMC Pulmonary Medicine

ISSN: 1471-2466

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