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Table 4 Baseline characteristics and respiratory function indices subdivided into groups according to median %FEV1.0

From: Vascular involvement in chronic thromboembolic pulmonary hypertension is associated with spirometry obstructive impairment

  %FEV1.0 < 83.6% %FEV1.0 83.6% p value
Age (years) 58.7 ± 1.7 62.2 ± 1.4 N.S
Male/female, n 19/48 8/60 0.0148*
Body weight (kg) 57.2 ± 1.5 52.8 ± 1.05 0.0339*
BMI (kg/m2) 22.4 ± 0.5 21.8 ± 0.3 N.S
WHO-FC (I: II: III: IV) 6/34/26/1 4/40/24/0 N.S
Type (Occult/Recurrent) 40/27 40/28 N.S
Hb (g/dL) 13.9 ± 0.2 13.6 ± 0.2 N.S
BNP (pg/mL) 296 ± 51 162 ± 27 0.0098**
CRP (g/dL) 0.27 ± 0.06 0.21 ± 0.05 0.0173*
ATIII (%) 97.4 ± 1.8 100.3 ± 1.6 N.S
Systolic SBP 123 ± 3 129 ± 2 0.0346*
Diastolic SBP 73 ± 2 74 ± 2 N.S
mPAP (mmHg) 45.1 ± 1.3 41.1 ± 1.2 0.0331*
PVR (dyne sec cm−5) 815 ± 45 689 ± 34 0.0334*
RAP (mmHg) 10.1 ± 0.53 7.65 ± 0.43 0.0008**
CO (L/min) 4.05 ± 0.14 4.23 ± 0.13 N.S
CI (L/min/m2) 2.51 ± 0.08 2.77 ± 0.09 0.0307*
CTA obstruction score 30.1 ± 1.3 21.6 ± 1.2 < 0.0001**
  1. Values are expressed as the mean ± standard error of the mean
  2. BMI, body mass index; WHO-FC, WHO-functional class; Hb, hemoglobin; BNP, brain natriuretic peptide; CRP, C-reactive protein; AT III, antithrombin III, SBP, systemic blood pressure; PAP, pulmonary arterial pressure; PVR, pulmonary vascular resistance; CO, cardiac output; CI, cardiac index
  3. *p < 0.05; **p < 0.01