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Table 4 Multivariate logistic regression analysis of risk factors for COPD coexisting OSA (AHI > 15 times per hour)

From: Predictors and outcomes of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in China

Variables β Wald P OR 95% CI
BMI (kg/m2) 0.161 26.794  < 0.001 1.175 1.104 ~ 1.251
Neck circumference 0.101 4.251  < 0.001 1.099 1.013 ~ 1.211
FEV1 0.023 2.086 0.149 1.023 0.991 ~ 1.057
FEV1 (%predicted) < 50% − 0.549 5.893 0.045 0.578 0.392 ~ 0.782
CAT scores 0.187 30.154  < 0.001 1.195 1.112 ~ 1.288
ESS scores 0.118 7.667  < 0.001 1.113 1.052 ~ 1.177
SBQ scores 0.188 13.866  < 0.001 1.206 1.119 ~ 1.301
HADS-A 0.201 27.956  < 0.001 1.275 1.126 ~ 1.432
HADS-D 0.198 28.012  < 0.001 1.243 1.120 ~ 1.401
Hypertension 0.309 30.442 0.037 1.831 1.357 ~ 2.321
Coronary heart disease 0.111 3.458 0.053 1.117 0.999 ~ 1.249
Diabetes 0.311 34.521  < 0.001 1.852 1.421 ~ 2.312
  1. Overlap syndrome (AHI > 15 times per hour) was considered as the dependent variable and age, BMI, neck circumference, FEV1, FEV1(%predicted) < 50%, CAT score, ESS score, SBQ scores, HADS-A scores, HADS-D scores, hypertension, coronary heart disease and diabetes as independent variables. BMI body mass index; FEV1 forced expiratory volume in 1 s; CAT COPD assessment test; ESS Epworth sleepiness scale; SBQ STOP-Bang; HADS-A Hospital Anxiety and Depression Scale for anxiety; HADS-D Hospital Anxiety and Depression Scale for depression.